• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

铅毒理学的政治问题及其对儿童造成的毁灭性后果。

The politics of lead toxicology and the devastating consequences for children.

作者信息

Rosner David, Markowitz Gerald

机构信息

Columbia University, Mailman School of Public Health, New York, USA.

出版信息

Am J Ind Med. 2007 Oct;50(10):740-56. doi: 10.1002/ajim.20435.

DOI:10.1002/ajim.20435
PMID:17486583
Abstract

At virtually every step in the history of the uncovering of lead's toxic qualities, resistance was shown by a variety of industrial interests to the association of lead and toxicity. During the first half of the last century, three primary means were used to undermine the growing body of evidence: first, the lead industry sought to control lead research by sponsoring and funding university research. In the 1920s, the General Motors Company, with the aide of DuPont and Standard Oil Companies, established the Kettering Labs, a research unit at the University of Cincinnati which, for many decades was largely supported by industry funds. In the same decade, the lead industry sponsored the research of Joseph Aub at Harvard who worked on neurophysiology of lead. A second way was to shape our understanding of lead itself, portraying it as an indispensable and healthful element essential for all modern life. Lead was portrayed as safe for children to use, be around, and even touch. The third way that lead was exempted from the normal public health measures and regulatory apparatus that had largely controlled phosphorus poisoning, poor quality food and meats and other potential public health hazards was more insidious and involved directly influencing the scientific integrity of the clinical observations and research. Throughout the past century tremendous pressure by the lead industry itself was brought to bear to quiet, even intimidate, researchers and clinicians who reported on or identified lead as a hazard. This article will draw on our previous work and add new documentation of the trajectory of industry attempts to keep out of the public view the tremendous threat of lead poisoning to children.

摘要

在揭示铅的毒性特质的历史进程中,几乎每一步都遭遇了来自各类工业利益集团的抵制,他们反对将铅与毒性联系起来。在上个世纪上半叶,主要采用了三种手段来削弱日益增多的证据:其一,铅行业试图通过资助大学研究来控制铅研究。20世纪20年代,通用汽车公司在杜邦公司和标准石油公司的协助下,成立了凯特林实验室,这是辛辛那提大学的一个研究单位,几十年来主要由行业资金资助。在同一十年里,铅行业资助了哈佛大学约瑟夫·奥布的研究,他致力于铅的神经生理学研究。第二种方式是塑造我们对铅本身的认知,将其描绘成现代生活不可或缺且有益健康的元素。铅被描绘成儿童使用、接触甚至触摸都是安全的。第三种方式是使铅免受那些在很大程度上控制了磷中毒、劣质食品和肉类以及其他潜在公共卫生危害的常规公共卫生措施和监管机构的管控,这种方式更为隐蔽,直接涉及影响临床观察和研究的科学诚信。在过去的一个世纪里,铅行业自身施加了巨大压力,以使那些报告或认定铅为危害的研究人员和临床医生保持沉默,甚至对他们进行恐吓。本文将借鉴我们之前的研究成果,并补充新的文献资料,以展现行业试图将铅中毒对儿童的巨大威胁排除在公众视野之外的轨迹。

相似文献

1
The politics of lead toxicology and the devastating consequences for children.铅毒理学的政治问题及其对儿童造成的毁灭性后果。
Am J Ind Med. 2007 Oct;50(10):740-56. doi: 10.1002/ajim.20435.
2
The Rhode Island lead paint lawsuit: where do we go from here?罗德岛含铅油漆诉讼案:我们从这里何去何从?
New Solut. 2006;16(4):353-63. doi: 10.2190/1448-H07K-KG70-3443.
3
Bad funding.
Nature. 2004 Nov 4;432(7013):1. doi: 10.1038/432001b.
4
"Cater to the children": the role of the lead industry in a public health tragedy, 1900-1955.“迎合儿童”:1900年至1955年主导产业在一场公共卫生悲剧中的角色
Am J Public Health. 2000 Jan;90(1):36-46. doi: 10.2105/ajph.90.1.36.
5
EPA accused of conflict of interest over chemicals study.美国环境保护局被指控在化学品研究中存在利益冲突。
Nature. 2004 Nov 4;432(7013):6. doi: 10.1038/432006a.
6
Environmental pediatrics and its impact on government health policy.环境儿科学及其对政府卫生政策的影响。
Pediatrics. 2004 Apr;113(4 Suppl):1146-57.
7
Big pharma and health care: unsolvable conflict of interests between private enterprise and public health.大型制药公司与医疗保健:私营企业与公共卫生之间无法解决的利益冲突。
Isr J Psychiatry Relat Sci. 2008;45(2):83-9; discussion 90-4.
8
Update on the clinical management of childhood lead poisoning.儿童铅中毒临床管理的最新进展。
Pediatr Clin North Am. 2007 Apr;54(2):271-94, viii. doi: 10.1016/j.pcl.2007.01.008.
9
Lead contamination in Uruguay: the "La Teja" neighborhood case.乌拉圭的铅污染:“拉泰亚”社区案例。
Rev Environ Contam Toxicol. 2008;195:93-115.
10
Lead in housing paints: an exposure source still not taken seriously for children lead poisoning in China.住宅涂料中的铅:在中国,这一暴露源仍未被视为儿童铅中毒的严重问题。
Environ Res. 2009 Jan;109(1):1-5. doi: 10.1016/j.envres.2008.09.003. Epub 2008 Oct 31.

引用本文的文献

1
Toolkit for detecting misused epidemiological methods.误用流行病学方法检测工具包。
Environ Health. 2021 Aug 19;20(1):90. doi: 10.1186/s12940-021-00771-6.
2
The transition to non-lead sporting ammunition and fishing weights: Review of progress and barriers to implementation.向无铅运动弹药和钓鱼铅块的转变:实施进展和障碍的回顾。
Ambio. 2019 Sep;48(9):925-934. doi: 10.1007/s13280-018-1132-x. Epub 2019 Jan 4.
3
Evidence Regarding the Impact of Conflicts of Interest on Environmental and Occupational Health Research.关于利益冲突对环境和职业健康研究影响的证据。
Curr Environ Health Rep. 2017 Jun;4(2):109-118. doi: 10.1007/s40572-017-0139-y.
4
Using mouse models of autism spectrum disorders to study the neurotoxicology of gene-environment interactions.使用自闭症谱系障碍的小鼠模型来研究基因-环境相互作用的神经毒理学。
Neurotoxicol Teratol. 2013 Mar-Apr;36:17-35. doi: 10.1016/j.ntt.2012.08.007. Epub 2012 Sep 7.