Rosner David, Markowitz Gerald
Columbia University, Mailman School of Public Health, New York, USA.
Am J Ind Med. 2007 Oct;50(10):740-56. doi: 10.1002/ajim.20435.
At virtually every step in the history of the uncovering of lead's toxic qualities, resistance was shown by a variety of industrial interests to the association of lead and toxicity. During the first half of the last century, three primary means were used to undermine the growing body of evidence: first, the lead industry sought to control lead research by sponsoring and funding university research. In the 1920s, the General Motors Company, with the aide of DuPont and Standard Oil Companies, established the Kettering Labs, a research unit at the University of Cincinnati which, for many decades was largely supported by industry funds. In the same decade, the lead industry sponsored the research of Joseph Aub at Harvard who worked on neurophysiology of lead. A second way was to shape our understanding of lead itself, portraying it as an indispensable and healthful element essential for all modern life. Lead was portrayed as safe for children to use, be around, and even touch. The third way that lead was exempted from the normal public health measures and regulatory apparatus that had largely controlled phosphorus poisoning, poor quality food and meats and other potential public health hazards was more insidious and involved directly influencing the scientific integrity of the clinical observations and research. Throughout the past century tremendous pressure by the lead industry itself was brought to bear to quiet, even intimidate, researchers and clinicians who reported on or identified lead as a hazard. This article will draw on our previous work and add new documentation of the trajectory of industry attempts to keep out of the public view the tremendous threat of lead poisoning to children.
在揭示铅的毒性特质的历史进程中,几乎每一步都遭遇了来自各类工业利益集团的抵制,他们反对将铅与毒性联系起来。在上个世纪上半叶,主要采用了三种手段来削弱日益增多的证据:其一,铅行业试图通过资助大学研究来控制铅研究。20世纪20年代,通用汽车公司在杜邦公司和标准石油公司的协助下,成立了凯特林实验室,这是辛辛那提大学的一个研究单位,几十年来主要由行业资金资助。在同一十年里,铅行业资助了哈佛大学约瑟夫·奥布的研究,他致力于铅的神经生理学研究。第二种方式是塑造我们对铅本身的认知,将其描绘成现代生活不可或缺且有益健康的元素。铅被描绘成儿童使用、接触甚至触摸都是安全的。第三种方式是使铅免受那些在很大程度上控制了磷中毒、劣质食品和肉类以及其他潜在公共卫生危害的常规公共卫生措施和监管机构的管控,这种方式更为隐蔽,直接涉及影响临床观察和研究的科学诚信。在过去的一个世纪里,铅行业自身施加了巨大压力,以使那些报告或认定铅为危害的研究人员和临床医生保持沉默,甚至对他们进行恐吓。本文将借鉴我们之前的研究成果,并补充新的文献资料,以展现行业试图将铅中毒对儿童的巨大威胁排除在公众视野之外的轨迹。