Woolf Alan D, Goldman Rose, Bellinger David C
Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA.
Pediatr Clin North Am. 2007 Apr;54(2):271-94, viii. doi: 10.1016/j.pcl.2007.01.008.
Childhood lead poisoning is still an enormous public health issue in the United States, affecting thousands of children and their families. New evidence suggests that even very low blood lead levels, less than 10 microg/dL, can be associated with neurologic injury. This article discusses characteristics of children at high risk for lead poisoning, unusual sources of lead contamination, and new aspects of lead's pathophysiology. It includes current thinking on the clinical management and prevention of childhood lead poisoning.
儿童铅中毒在美国仍然是一个严重的公共卫生问题,影响着成千上万的儿童及其家庭。新证据表明,即使血铅水平非常低,低于10微克/分升,也可能与神经损伤有关。本文讨论了铅中毒高危儿童的特征、铅污染的异常来源以及铅病理生理学的新方面。它包括目前对儿童铅中毒临床管理和预防的看法。