Collins Byron E, Anslyn Eric V
Department of Chemistry and Biochemistry, The University of Texas at Austin, Austin, TX 78712, USA.
Chemistry. 2007;13(17):4700-8. doi: 10.1002/chem.200700153.
Nature's use of sensor arrays in the mammalian olfactory and gustatory systems has encouraged supramolecular chemists to take a new approach to molecular recognition. Pattern-based recognition involves the use of sensor arrays to create fingerprints for analytes. The use of sensing arrays has paved the way for systems capable of identifying biological analytes that would have been difficult targets using the traditional "lock-and-key" approach to sensor design.
自然界在哺乳动物嗅觉和味觉系统中对传感器阵列的运用,促使超分子化学家采用一种新的分子识别方法。基于模式的识别涉及使用传感器阵列来为分析物创建指纹图谱。传感阵列的使用为能够识别生物分析物的系统铺平了道路,而使用传统的“锁钥”式传感器设计方法很难实现对这些生物分析物的识别。