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血液成分的安全处理与输注:实用概念综述

Safe handling and administration of blood components: review of practical concepts.

作者信息

Osby Melanie A, Saxena Sunita, Nelson Janice, Shulman Ira

机构信息

Department of Pathology, Los Angeles County-University of Southern California Medical Center, Los Angeles 90303, USA.

出版信息

Arch Pathol Lab Med. 2007 May;131(5):690-4. doi: 10.5858/2007-131-690-SHAAOB.

DOI:10.5858/2007-131-690-SHAAOB
PMID:17488153
Abstract

CONTEXT

The more advanced we become, the more evident are the infectious and noninfectious risks of the blood supply. Infectious risks are somewhat straightforward and are addressed by implementing stricter donor criteria and testing. The noninfectious risks, however, are more complicated. Each step in the transfusion process, beginning with the physician who orders a transfusion to the actual transfusion of the component, is subject to adverse outcomes and increases the noninfectious risks of transfusion. The challenges to provide the safest blood possible with zero risk have resulted in the implementation of stringent standards from both the American Association of Blood Banks and the Joint Commission on Accreditation of Healthcare Organizations.

OBJECTIVE

A series of case scenarios serve as the basis for discussion of the risks, which affect the safety and administration of blood components, inherent in the transfusion process.

DATA SOURCES

Journals, textbooks, Internet.

CONCLUSIONS

The transfusion process is a complex multistep process with inherent risks. Infectious risks of transfusion are being adequately addressed such that the noninfectious risks of transfusion are becoming much more evident. Patient safety can be compromised if each step of the transfusion process is not completed according to established policies and procedures at each individual institution.

摘要

背景

我们越进步,血液供应的感染性和非感染性风险就越明显。感染性风险在某种程度上较为直接,可通过实施更严格的献血者标准和检测来应对。然而,非感染性风险则更为复杂。输血过程中的每一步,从开具输血医嘱的医生到实际输注血液成分,都可能出现不良后果,并增加输血的非感染性风险。要提供零风险的最安全血液面临诸多挑战,这导致美国血库协会和医疗保健机构认证联合委员会都实施了严格的标准。

目的

一系列案例场景作为讨论输血过程中影响血液成分安全性和管理的风险的基础。

数据来源

期刊、教科书、互联网。

结论

输血过程是一个复杂的多步骤过程,存在固有风险。输血的感染性风险已得到充分应对,以至于输血的非感染性风险变得更加明显。如果输血过程的每一步都未按照各机构既定的政策和程序完成,患者安全可能会受到损害。

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