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双氯芬酸诱发的血小板减少性紫癜伴肾和肝受累。

Diclofenac-induced thrombocytopenic purpura with renal and hepatic involvement.

作者信息

Bondeson J, Berglund S

机构信息

Department of Medicine, Malmö General Hospital, University of Lund, Sweden.

出版信息

J Intern Med. 1991 Dec;230(6):543-7. doi: 10.1111/j.1365-2796.1991.tb00487.x.

DOI:10.1111/j.1365-2796.1991.tb00487.x
PMID:1748862
Abstract

A case of diclofenac-induced thrombocytopenic purpura in a 59-year-old woman is described. Unlike the majority of earlier cases, ours was associated with renal insufficiency and jaundice. Despite the dramatic clinical picture, with severe thrombocytopenia and marked renal insufficiency, the prognosis appears to be excellent, as is shown in our case and in similar ones reported in the literature. A high dose of steroids is the treatment of choice.

摘要

本文描述了一例59岁女性因双氯芬酸导致血小板减少性紫癜的病例。与大多数早期病例不同,我们的病例伴有肾功能不全和黄疸。尽管临床表现严重,出现严重血小板减少和明显肾功能不全,但正如我们的病例以及文献中报道的类似病例所示,预后似乎良好。大剂量类固醇是首选治疗方法。

相似文献

1
Diclofenac-induced thrombocytopenic purpura with renal and hepatic involvement.双氯芬酸诱发的血小板减少性紫癜伴肾和肝受累。
J Intern Med. 1991 Dec;230(6):543-7. doi: 10.1111/j.1365-2796.1991.tb00487.x.
2
[A case of rheumatoid arthritis complicated with idiopathic thrombocytopenic purpura].
Rinsho Ketsueki. 1988 Mar;29(3):359-63.
3
Thrombotic thrombocytopenic purpura during penicillamine therapy in rheumatoid arthritis.类风湿关节炎患者青霉胺治疗期间发生血栓性血小板减少性紫癜。
Arch Intern Med. 1983 Jul;143(7):1487-8.
4
[Case of thrombocytopenic purpura with fulminant course presumably caused by treatment of rheumatoid arthritis with gold salts].[可能由金盐治疗类风湿关节炎引发的暴发性血小板减少性紫癜病例]
Wiad Lek. 1975 Feb 15;28(4):295-9.
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Gold induced thrombocytopenic purpura.金所致血小板减少性紫癜
Conn Med. 1974 Nov;38(11):592-4.
6
[Cholestatic hepatitis and acute kidney insufficiency during treatment with diclofenac].
Ann Gastroenterol Hepatol (Paris). 1989 Nov;25(6):257-8.
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Thrombocytopenic purpura associated with piroxicam.与吡罗昔康相关的血小板减少性紫癜。
Clin Exp Rheumatol. 1987 Jul-Sep;5(3):298-300.
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Diclofenac-associated acute renal failure. Report of 2 cases.双氯芬酸相关的急性肾衰竭。2例报告。
Nephron. 1985;40(4):491-3. doi: 10.1159/000183528.
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Thrombocytopenia and purpura-like lesions associated with clopidogrel.与氯吡格雷相关的血小板减少症和紫癜样病变
Ital Heart J. 2001 Dec;2(12):935-7.
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Subdural hematoma secondary to immune thrombocytopenic purpura: case report.免疫性血小板减少性紫癜继发硬膜下血肿:病例报告
Neurosurgery. 1986 Oct;19(4):635-6. doi: 10.1227/00006123-198610000-00023.

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The effect of diclofenac Na (Voltarol) on the haematopoietic cells of bone marrow in sheep.双氯芬酸钠(扶他林)对绵羊骨髓造血细胞的影响。
Vet Res Commun. 1998 Sep;22(6):401-3. doi: 10.1023/a:1006149429198.