Bhandari Rashna, Chakraborty Anutosh, Snyder Solomon H
Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Cell Metab. 2007 May;5(5):321-3. doi: 10.1016/j.cmet.2007.04.008.
Physiologic roles of highly phosphorylated inositol phosphates, including those containing pyrophosphate groups, have been the focus of much recent interest. In the April 6, 2007 issue of Science, two papers (Lee et al., 2007; Mulugu et al., 2007) demonstrate the occurrence of a novel inositol pyrophosphate molecule in yeast and elucidate its role in phosphate homeostasis.
高度磷酸化的肌醇磷酸酯(包括那些含有焦磷酸基团的)的生理作用,一直是近期众多研究的焦点。在2007年4月6日的《科学》杂志上,两篇论文(Lee等人,2007年;Mulugu等人,2007年)证明了酵母中一种新型肌醇焦磷酸分子的存在,并阐明了其在磷酸盐稳态中的作用。