Brudno Michael, Poliakov Alexander, Minovitsky Simon, Ratnere Igor, Dubchak Inna
Department of Computer Science, Banting and Best Department of Medical Research, University of Toronto, 6 King's College Road, Toronto, ON, Canada M5S 3G4.
Nucleic Acids Res. 2007 Jul;35(Web Server issue):W669-74. doi: 10.1093/nar/gkm279. Epub 2007 May 8.
The VISTA portal for comparative genomics is designed to give biomedical scientists a unified set of tools to lead them from the raw DNA sequences through the alignment and annotation to the visualization of the results. The VISTA portal also hosts the alignments of a number of genomes computed by our group, allowing users to study the regions of their interest without having to manually download the individual sequences. Here we describe various algorithmic and functional improvements implemented in the VISTA portal over the last 2 years. The VISTA Portal is accessible at http://genome.lbl.gov/vista.
用于比较基因组学的VISTA门户旨在为生物医学科学家提供一套统一的工具，引导他们从原始DNA序列开始，经过比对和注释，直至结果可视化。VISTA门户还托管了我们团队计算的多个基因组的比对结果，用户无需手动下载单个序列就能研究他们感兴趣的区域。在此，我们描述了过去两年在VISTA门户中实现的各种算法和功能改进。可通过http://genome.lbl.gov/vista访问VISTA门户。
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