Horiot Jean-Claude
Centre de Lutte Contre le Cancer G.F. Leclerc, Dijon, France.
J Clin Oncol. 2007 May 10;25(14):1930-5. doi: 10.1200/JCO.2006.10.5312.
Delivering radiotherapy to the geriatric cancer patient raises several questions: Are there objective reasons to consider the elderly population as potentially more vulnerable to radiation therapy than younger people? In practice, how are geriatric patients treated when radiotherapy is indicated? Recent data from French tumor registries on rectal cancers are reviewed to illustrate the evolution of the practices during a 20-year period up to 2000. Is there a changing landscape in radiotherapy research protocols in the elderly? Thirty-one European Organisation for Research and Treatment of Cancer (Brussels, Belgium) radiotherapy protocols are analyzed regarding compliance to the 1996 recommendation of having no upper age limit when other eligibility factors are fulfilled. To conclude, specific recommendations for optimal radiotherapeutic management of geriatric patients are made for some common cancers in the elderly.
是否存在客观理由认为老年人群体比年轻人更容易受到放射治疗的影响？在实际操作中，当需要进行放射治疗时，老年患者是如何接受治疗的？回顾了法国肿瘤登记处关于直肠癌的最新数据，以说明截至2000年的20年期间治疗方法的演变。老年放射治疗研究方案是否正在发生变化？分析了31项欧洲癌症研究与治疗组织（比利时布鲁塞尔）的放射治疗方案，以确定其是否符合1996年提出的在满足其他入选标准时无年龄上限的建议。最后，针对老年患者常见癌症的最佳放射治疗管理提出了具体建议。
