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老年患者的放射治疗:一项针对转诊至37家意大利放射治疗中心的2060例患者的多中心前瞻性研究。

Radiotherapy in the elderly: a multicentric prospective study on 2060 patients referred to 37 Italian radiation therapy centers.

作者信息

Olmi P, Ausili-Cefaro G

机构信息

Dipartimento di Fisiopatologia Clinica, Università di Firense, Italy.

出版信息

Rays. 1997 Jan-Mar;22(1 Suppl):53-6.

PMID:9250015
Abstract

60-70% of all cancers will develop in the year 2000 in persons aged 65 and over. Radiation therapy will play a major role in the treatment of cancer, especially in the elderly. The Italian "Geriatric Radiation Oncology Group" (GROG) performed in 1994 a prospective study, in order to assess the characteristics of any old cancer patient referred to radiation oncology centers (age, gender performance status, comorbidity, activities of daily living, family status) and the main features of the tumor in that patient. In about 6 months 2060 patients aged 70 and over entered the study, of whom 1809 were treated with radiotherapy alone, with curative intent in 563 patients, in combination with surgery and/or chemotherapy in 476 and with palliative intent in 769 patients. Most patients had grade 0-1 acute toxicity.

摘要

2000年,60%至70%的癌症将发生在65岁及以上的人群中。放射治疗将在癌症治疗中发挥重要作用,尤其是在老年患者中。意大利“老年放射肿瘤学组”(GROG)于1994年进行了一项前瞻性研究,以评估转诊至放射肿瘤学中心的老年癌症患者的特征(年龄、性别、体能状态、合并症、日常生活活动能力、家庭状况)以及该患者肿瘤的主要特征。在大约6个月的时间里,2060名70岁及以上的患者进入了该研究,其中1809名患者仅接受了放射治疗,563名患者接受治疗的目的是治愈,476名患者接受了手术和/或化疗联合治疗,769名患者接受治疗的目的是姑息治疗。大多数患者出现0-1级急性毒性反应。

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