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评估儿童精神药物的副作用:一项可靠性研究。

Assessing psychotropic medication side effects among children. A reliability study.

作者信息

Garvey C A, Gross D, Freeman L

出版信息

J Child Adolesc Psychiatr Ment Health Nurs. 1991 Oct-Dec;4(4):127-31. doi: 10.1111/j.1744-6171.1991.tb00509.x.

DOI:10.1111/j.1744-6171.1991.tb00509.x
PMID:1748956
Abstract

The Dosage Record Treatment Emergent Symptom Scale (DOTES) is a rating scale for measuring the presence and intensity of psychotropic medication side effects. Studies to evaluate its reliability have not been published. The purposes of this pilot study are to (1) develop a protocol for training raters to use the DOTES, (2) assess inter-rater agreement, 3) examine the reasons for disagreement among raters to clarify training procedures and symptom definitions, and (4) further refine this instrument for use in clinical and research settings. Five nurses were trained to use the DOTES to rate the absence or presence and intensity of specific medication side effects. After training, Raters 1, 2, and 3 watched a videotape of a nurse interviewing a 13-year-old child and completed the DOTES rating scale. There was agreement on the intensities of 6 (67%) of the 9 symptoms identified as present and agreement on 17 (89%) of the 19 symptoms identified as absent. Process tracings were conducted on the ratings of Nurses 4 and 5 to elicit the criteria they used to determine their ratings. The results of the process tracings were used to identify ambiguities that led to disagreement among raters so that the training protocol and interview could be improved.

摘要

剂量记录治疗突发症状量表(DOTES)是一种用于衡量精神药物副作用的存在情况和严重程度的评定量表。评估其信度的研究尚未发表。这项初步研究的目的是:(1)制定培训评分者使用DOTES的方案;(2)评估评分者间的一致性;(3)探究评分者之间存在分歧的原因,以明确培训程序和症状定义;(4)进一步完善该工具,以便在临床和研究环境中使用。五名护士接受了使用DOTES对特定药物副作用的有无及严重程度进行评分的培训。培训后,评分者1、2和3观看了一名护士采访一名13岁儿童的录像带,并完成了DOTES评定量表。在确定为存在的9种症状中,有6种(67%)症状的严重程度达成了一致;在确定为不存在的19种症状中,有17种(89%)症状达成了一致。对评分者4和5的评分进行了过程追踪,以了解他们用于确定评分的标准。过程追踪的结果用于识别导致评分者之间存在分歧的模糊之处,从而改进培训方案和访谈。

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