Lever Michael, Atkinson Wendy, George Peter M, Chambers Stephen T
Clinical Biochemistry Unit, Canterbury Health Laboratories, Christchurch School of Medicine and Health Sciences, Christchurch, New Zealand.
Clin Biochem. 2007 Jul;40(11):798-801. doi: 10.1016/j.clinbiochem.2007.03.009. Epub 2007 Mar 28.
Does abnormal betaine excretion persist?
Patients (10) with abnormal excretion in 1998 were recalled in 2005. Subsequent urine samples were collected on 4 days from persistently abnormal subjects.
Half the 1998 abnormal patients were abnormal in 2005. Only 1/20 controls was abnormal (p=0.015). All patients with abnormal excretion in 1998 and 2005 had abnormal excretion on successive days while no controls did.
High betaine excretion may be chronic and a health risk.
异常的甜菜碱排泄是否持续存在？
2005年召回了1998年排泄异常的患者（共10例）。从持续异常的受试者中收集了4天的后续尿液样本。
1998年排泄异常的患者中有一半在2005年仍异常。对照组中只有1/20异常（p = 0.015）。1998年和2005年排泄异常的所有患者连续几天排泄均异常，而对照组则无此情况。
高甜菜碱排泄可能是慢性的，且存在健康风险。
