植物中与DNA或组蛋白修饰变化无关的表观遗传转变。
Epigenetic transitions in plants not associated with changes in DNA or histone modification.
作者信息
Nishimura Taisuke, Paszkowski Jerzy
机构信息
Laboratory of Plant Genetics, University of Geneva, CH-1211 Geneva 4, Switzerland.
出版信息
Biochim Biophys Acta. 2007 May-Jun;1769(5-6):393-8. doi: 10.1016/j.bbaexp.2007.03.002. Epub 2007 Mar 12.
Covalent modifications of DNA and histones correlate with chromatin compaction and with its transcriptional activity and contribute to mitotic and meiotic heritability of epigenetic traits. However, there are intriguing examples of the transition of epigenetic states in plants that appear to be uncoupled from the conventional mechanisms of chromatin-mediated regulation of transcription. Further study of the molecular mechanism and biological significance of such atypical epigenetic regulation may uncover novel aspects of epigenetic gene regulation and better define its role in plant development and environmental adaptation.
DNA和组蛋白的共价修饰与染色质压缩及其转录活性相关，并有助于表观遗传性状的有丝分裂和减数分裂遗传。然而，在植物中存在一些有趣的表观遗传状态转变的例子，这些转变似乎与染色质介导的转录调控的传统机制无关。对这种非典型表观遗传调控的分子机制和生物学意义的进一步研究，可能会揭示表观遗传基因调控的新方面，并更好地界定其在植物发育和环境适应中的作用。
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