Meyer Daniel, Schmid Hans-Peter, Engeler Daniel S
Klinik für Urologie, Kantonsspital St. Gallen, St. Gallen, Schweiz.
Wien Med Wochenschr. 2007;157(7-8):162-9. doi: 10.1007/s10354-007-0381-2.
Treatment and follow up of bladder cancer strongly depends on stage and differentiation of the tumour. Superficial bladder tumours can mostly be controlled by transurethral resection followed by early intravesical application of a chemotherapeutic agent and a further close meshed follow-up. Generally, for muscle-invasive tumours radical cystectomy is indicated, whereas organ-spearing treatment due to combined therapeutic concepts can be offered in selected cases. For advanced and metastatic tumours, despite good response of bladder cancer to chemotherapy, prognosis is still poor. However, implementation of new chemotherapeutic agents indicate a trend towards improved survival rates.
膀胱癌的治疗与随访很大程度上取决于肿瘤的分期和分化程度。浅表性膀胱肿瘤大多可通过经尿道切除术控制,随后早期膀胱内应用化疗药物并进行更密切的密集随访。一般来说,对于肌层浸润性肿瘤,建议行根治性膀胱切除术,而在某些特定情况下,由于综合治疗理念可提供保留器官的治疗。对于晚期和转移性肿瘤,尽管膀胱癌对化疗反应良好,但预后仍然很差。然而,新化疗药物的应用显示出生存率提高的趋势。