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水貂血清α2-脂蛋白的3种新同种异型——Lpm 6、Lpm 7、Lpm 8

[3 new allotypes of mink blood serum alpha2-lipoproteins--Lpm 6, Lpm 7, Lpm 8].

作者信息

Baranov O K, Savina M A, Beliaev D K

出版信息

Genetika. 1975;11(9):32-7.

PMID:174971
Abstract

Three new allotypes were discovered in mink sera by means of isoimmunization. Based on the results of identifications, they were referred to the Lpm system of serum alpha2-lipoprotein. They were designated as Lpm 6, Lpm 7 and Lpm 8. The allotyping of serum samples from 342 minks made possible to establish a relation between Lpm 7 and Lpm 8 using the chi2 method; it was also found that these two allotypes related to each of the first five Lpm as well as to their phenotypes, which was described earlier. There was a significant dependence of the expression of Lpm 6 on Lpm 5 indicating a genetic relation between Lpm 6 and other allotypes. The detection of Lpm 6, 7 and 8, which are the most likely under the control of the same gene (or a sustem of genes) as Lpm 1, 2, 3 and 5, is an evidence for the complex structure of the Lpm locus.

摘要

通过同种免疫法在水貂血清中发现了三种新的同种异型。根据鉴定结果,它们被归入血清α2 -脂蛋白的Lpm系统。它们被命名为Lpm 6、Lpm 7和Lpm 8。对342只水貂的血清样本进行同种异型分型,使得利用卡方方法确定Lpm 7和Lpm 8之间的关系成为可能;还发现这两种同种异型与前五种Lpm及其表型有关,这在之前已有描述。Lpm 6的表达对Lpm 5有显著依赖性,表明Lpm 6与其他同种异型之间存在遗传关系。Lpm 6、7和8很可能与Lpm 1、2、3和5受同一基因(或一组基因)控制,这一发现证明了Lpm基因座的复杂结构。

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