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[水貂高密度血清α2-脂蛋白7种Lpm系统同种异型的遗传控制]

[Genetic control over 7 Lpm-system allotypes of very high-density serum alpha2-lipoprotein the mink].

作者信息

Baranov O K, Beliaev D K

出版信息

Genetika. 1978 Mar;14(3):424-37.

PMID:205484
Abstract

Population and hybridological analyses have demonstrated that the alloantigenic markers of very high density alpha2-lipoprotein of mink serum, Lpm7 and Lpm8, along with Lpm1, Lpm2, Lpm3, Lpm4, Lpm5, belong to a common immunogenetic system. 21 Lpm-phenotypes are determined at least by 36 genotypes; each of the 11 phenotypes is conditioned by a single genotype, each of the remaining 10 are conditioned by 2, 3 or 4 genotypes. The Lpm allotypes and allogroups are coded by the genetic units Lpm8, Lpm4, Lpm4,8, Lpm4,7, Lpm3,4,8, Lpm1,8, Lpm1,2,7, Lpm2,4,5,7, which behave as alleles. The last, six seem to be haploid sets of closely linked genes.

摘要

群体和杂交分析表明,水貂血清中极高密度α2-脂蛋白的同种抗原标记Lpm7和Lpm8,与Lpm1、Lpm2、Lpm3、Lpm4、Lpm5属于一个共同的免疫遗传系统。至少由36种基因型决定了21种Lpm表型;11种表型中的每一种由单一基因型决定,其余10种表型中的每一种由2种、3种或4种基因型决定。Lpm同种异型和同种组由遗传单位Lpm8、Lpm4、Lpm4,8、Lpm4,7、Lpm3,4,8、Lpm1,8、Lpm1,2,7、Lpm2,4,5,7编码,这些遗传单位表现为等位基因。最后六个似乎是紧密连锁基因的单倍体组。

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