播散性传染性软疣作为免疫重建炎症综合征的一种表现。

Exuberant molluscum contagiosum as a manifestation of the immune reconstitution inflammatory syndrome.

作者信息

Pereira Bárbara, Fernandes Cândida, Nachiambo Ermelinda, Catarino Ma Carmo, Rodrigues Ana, Cardoso Jorge

机构信息

Hospital de Curry Cabral, Dermatology Department, Lisbon, Portugal.

出版信息

Dermatol Online J. 2007 May 1;13(2):6.

PMID:17498425

Abstract

Immune reconstitution inflammatory syndrome (IRIS) is a recently described entity in which severely immunodepressed HIV patients, after being started on HAART, develop inflammatory reactions to several pathogens. We present a patient who developed extensive Molluscum Contagiosum (MC) lesions shortly after being started on HAART. With the progression of immunoreconstitution, the lesions healed spontaneously. Molluscum contagiosum lesions are presumably common in IRIS but underreported. We point out this case for its striking clinical picture and well-documented relation to immunoreconstitution to draw attention to this IRIS manifestation.

摘要

免疫重建炎症综合征（IRIS）是一种最近才被描述的病症，在该病症中，严重免疫抑制的HIV患者在开始接受高效抗逆转录病毒治疗（HAART）后，会对多种病原体产生炎症反应。我们报告了一名患者，该患者在开始HAART治疗后不久就出现了广泛的传染性软疣（MC）皮损。随着免疫重建的进展，皮损自行愈合。传染性软疣皮损在IRIS中可能很常见，但报道不足。我们指出这个病例是因其显著的临床表现以及与免疫重建的明确关系，以引起对这种IRIS表现的关注。