Zhang Jinghu, Xiong Yuanzhu, Zuo Bo, Lei Minggang, Jiang Siwen, Li Feng'e, Zheng Rong, Li Jialian, Xu Dequan
Key Laboratory of Swine Genetics and Breeding, Ministry of Agriculture, College of Animal Science and Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China.
J Genet Genomics. 2007 Apr;34(4):307-14. doi: 10.1016/S1673-8527(07)60032-0.
Quantitative trait loci (QTL) were detected for 8 internal organ traits, 3 carcass length traits, and teat number trait in 214 pigs in a resource population that included 180 F(2) individuals. A total of 39 microsatellite markers were examined on SSC4, SSC6, SSC7, SSC8, and SSC13. The genetic traits included heart weight (HW), lung weight (LW), liver and gallbladder weight (LGW), spleen weight (SPW), stomach weight (STW), small intestine weight (SIW), large intestine weight (LIW), kidney weight (KW), carcass length to the first cervical vertebra (CL1), carcass length to the first thoracic vertebra (CL2), rib numbers (RNS), and teat numbers (TNS). Results indicated that, 3 highly significant QTL (P <or= 0.01 at chromosome-wise level) for HW (at 30 cM on SSC6), RNS (at 115 cM on SSC7), TNS (at 110 cM on SSC7), and 6 significant QTL (P <or= 0.05 at chromosome-wise level) for LW (at 119 cM on SSC13), LGW (at 94 cM on SSC6), SPW (at 106 cM on SSC8), SIW (0 cM on SSC4), LIW (170 cM on SSC 4), and TNS (at 95 cM on SSC6) were detected. The phenotypic variances for which these QTL were accounted ranged from 0.04 % to 14.06 %. Most of these QTL had not been previously reported.
在一个包含180个F(2)个体的资源群体中的214头猪中，检测了8个内脏器官性状、3个胴体长度性状和乳头数性状的数量性状基因座（QTL）。在猪的4号、6号、7号、8号和13号染色体上共检测了39个微卫星标记。遗传性状包括心脏重量（HW）、肺重量（LW）、肝脏和胆囊重量（LGW）、脾脏重量（SPW）、胃重量（STW）、小肠重量（SIW）、大肠重量（LIW）、肾脏重量（KW）、到第一颈椎的胴体长度（CL1）、到第一胸椎的胴体长度（CL2）、肋骨数（RNS）和乳头数（TNS）。结果表明，检测到3个极显著的QTL（在染色体水平上P≤0.01），分别为心脏重量（位于6号染色体30 cM处）、肋骨数（位于7号染色体115 cM处）、乳头数（位于7号染色体110 cM处）；6个显著的QTL（在染色体水平上P≤0.05），分别为肺重量（位于13号染色体119 cM处）、肝脏和胆囊重量（位于6号染色体94 cM处）、脾脏重量（位于8号染色体106 cM处）、小肠重量（位于4号染色体0 cM处）、大肠重量（位于4号染色体170 cM处）和乳头数（位于6号染色体95 cM处）。这些QTL所解释的表型变异范围为0.04%至14.06%。这些QTL大多数以前未曾报道过。
