Duran F, Torres J, Charro A, Bosch A O
Horm Metab Res. 1975 Nov;7(6):499-501. doi: 10.1055/s-0028-1093712.
The adrenal response as measured by the plasmatic changes in 11-hydroxy-corticosteroid (11-OHCS) concentration following the administration of a synthetic octadecapeptide (C-41795-Ba) was compared in 17 normal young males with that obtained with the commercially available tetracosactrin. C-41795-Ba polypeptide shows a higher potency than tetracosactrin. Its effects are longer lasting when administered intravenously which indicates a significant local inactivation of the polypeptide.
通过测量17名正常年轻男性在给予合成十八肽（C-41795-Ba）后11-羟基皮质类固醇（11-OHCS）浓度的血浆变化来评估肾上腺反应，并将其与使用市售的二十四肽促皮质素所获得的反应进行比较。C-41795-Ba多肽显示出比二十四肽促皮质素更高的效力。静脉注射时其作用持续时间更长，这表明该多肽存在显著的局部失活。
