Rao Sheng-Xiang, Zeng Meng-Su, Chen Cai-Zhong, Li Ren-Chen, Zhang Shu-Jie, Xu Jian-Ming, Hou Ying-Yong
Department of Radiology, Zhongshan Hospital, Fudan University, 180 Fenglin Road, 200032 Shanghai, People's Republic of China.
Eur J Radiol. 2008 Feb;65(2):299-303. doi: 10.1016/j.ejrad.2007.04.001. Epub 2007 May 10.
To evaluate the clinical value of diffusion-weighted imaging (DWI) in combination with T(2)-weighted imaging (T(2)WI) for the detection of rectal cancer as compared with T(2)WI alone.
Forty-five patients with rectal cancer and 20 without rectal cancer underwent DWI with parallel imaging and T(2)WI on a 1.5 T scanner. Images were independently reviewed by two readers blinded to the results to determine the detectability of rectal cancer. The detectability of T(2)W imaging without and with DW imaging was assessed by means of receiver operating characteristic analysis. The interobserver agreement between the two readers was calculated with kappa statistics.
The ROC analysis showed that each of two readers achieved more accurate results with T(2)W imaging combined with DW imaging than with T(2)W imaging alone significantly. The A(z) values for the two readers for each T(2)WI and T(2)WI combined with DWI were 0.918 versus 0.991 (p=0.0494), 0.934 versus 0.997 (p=0.0475), respectively. The values of kappa were 0.934 for T(2)WI and 0.948 for T(2)WI combined with DWI between the two readers.
The addition of DW imaging to conventional T(2)W imaging provides better detection of rectal cancer.
评估扩散加权成像（DWI）联合T2加权成像（T2WI）用于检测直肠癌的临床价值，并与单独使用T2WI进行比较。
45例直肠癌患者和20例非直肠癌患者在1.5T扫描仪上进行了并行成像的DWI和T2WI检查。由两名对结果不知情的阅片者独立评估图像，以确定直肠癌的可检测性。通过接受者操作特征分析评估T2WI单独及联合DWI时的可检测性。用kappa统计量计算两名阅片者之间的观察者间一致性。
ROC分析显示，两名阅片者中每一位在T2WI联合DWI成像时均比单独使用T2WI成像能显著获得更准确的结果。两名阅片者对于每种T2WI及T2WI联合DWI的A(z)值分别为0.918对0.991（p=0.0494）、0.934对0.997（p=0.0475）。两名阅片者之间T2WI的kappa值为0.934，T2WI联合DWI的kappa值为0.948。
在传统T2WI成像基础上增加DWI成像能更好地检测直肠癌。
