Nitta S, Yambe T, Katahira Y, Sonobe T, Naganuma S, Akiho H, Chiba S, Kakinuma Y, Matsuzawa H, Hayashi H
Department of Medical Engineering and Cardiology, Tohoku University, Sendai, Japan.
Sci Rep Res Inst Tohoku Univ Med. 1991 Jul;38(1):19-27.
TH-7B pneumatically driven sac-type ventricular assist device and drive system including automatic control system were developed and evaluated in the chronic animal experiments. The blood-contacting surfaces of the blood pump are coated with either Cardiothane or Cardiomat. In the chronic experiments using adult goats, only one of fifteen goats showed sudden thrombus formation after 34 pumping days. No gross findings of thrombus formation were observed in any of the cases, except for a thin circular thrombus at the junction of the connectors and the sac of the blood pump. These results suggest that antithrombogenicity of this system was satisfactory for clinical use.
研发了TH - 7B气动囊式心室辅助装置及包括自动控制系统在内的驱动系统，并在慢性动物实验中进行了评估。血泵的血液接触表面涂有Cardiothane或Cardiomat。在使用成年山羊的慢性实验中，15只山羊中只有1只在泵血34天后出现突然血栓形成。除血泵连接器与囊的连接处有一薄环形血栓外，在任何病例中均未观察到血栓形成的大体表现。这些结果表明，该系统的抗血栓形成性对于临床应用而言是令人满意的。
