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一组住院老年患者自我报告的流感和肺炎球菌疫苗接种状况的有效性

Validity of self-reported influenza and pneumococcal vaccination status among a cohort of hospitalized elderly inpatients.

作者信息

Skull Susan A, Andrews Ross M, Byrnes Graham B, Kelly Heath A, Nolan Terence M, Brown Graham V, Campbell Donald A

机构信息

Department of Paediatrics, University of Melbourne, Royal Children's Hospital, Flemington Road, Parkville, Victoria 3052, Australia.

出版信息

Vaccine. 2007 Jun 15;25(25):4775-83. doi: 10.1016/j.vaccine.2007.04.015. Epub 2007 Apr 26.

Abstract

Use of self-reported vaccination status is commonplace in assessing vaccination coverage for public health programs and individuals, yet limited validity data exist. We compared self-report with provider records for pneumococcal (23vPPV) and influenza vaccine for 4887 subjects aged>or=65 years from two Australian hospitals. Self-reported influenza vaccination status had high sensitivity (98%), positive predictive value (PPV) (88%) and negative predictive value (NPV) (91%), but low specificity (56%). Self-reported 23vPPV (previous 5 years) had a sensitivity of 84%, specificity 77%, PPV 85% and NPV 76%. Clinicians can be reasonably confident of self-reported influenza vaccine status, and for positive self-report for 23vPPV in this setting. For program evaluation, self-reported influenza vaccination coverage among inpatients overestimates true coverage by about 10% versus 1% for 23vPPV. Self-report remains imperfect and whole-of-life immunisation registers a preferable goal.

摘要

在评估公共卫生项目和个人的疫苗接种覆盖率时,使用自我报告的疫苗接种状况很常见,但有效的数据有限。我们比较了来自两家澳大利亚医院的4887名年龄≥65岁受试者的肺炎球菌(23价肺炎多糖疫苗)和流感疫苗自我报告情况与医疗机构记录。自我报告的流感疫苗接种状况具有较高的敏感性(98%)、阳性预测值(PPV)(88%)和阴性预测值(NPV)(91%),但特异性较低(56%)。自我报告的23价肺炎多糖疫苗(过去5年)敏感性为84%,特异性为77%,PPV为85%,NPV为76%。临床医生可以对自我报告的流感疫苗接种状况有合理的信心,在这种情况下对于23价肺炎多糖疫苗的自我报告阳性也是如此。对于项目评估,住院患者中自我报告的流感疫苗接种覆盖率高估了实际覆盖率约10%,而23价肺炎多糖疫苗高估了1%。自我报告仍然存在缺陷,终身免疫登记是一个更理想的目标。

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