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未破裂颅内动脉瘤治疗后慢性头痛的改善

Improvement of chronic headache after treatment of unruptured intracranial aneurysms.

作者信息

Kong Doo-Sik, Hong Seung-Chyul, Jung Young-Jo, Kim Jong Soo

机构信息

Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.

出版信息

Headache. 2007 May;47(5):693-7. doi: 10.1111/j.1526-4610.2006.00630.x.

Abstract

OBJECTIVE

The objective of this study is to determine the incidence, character, and outcome of headache in patients with unruptured intracranial aneurysms who had been treated to avoid the risk of rupture.

BACKGROUND

There are a variety of clinical manifestations associated with unruptured intracranial aneurysms. Among them, chronic headache is the most common presenting and/or accompanying symptom.

METHODS

Among the 137 patients with unruptured aneurysms who had been treated, we collected 81 patients excluding 30 on the basis of inclusion criteria. Twenty-six patients were lost to follow-up. We collected data by medical record review and a telephone survey. Included in the information collected was the analysis of presenting symptom, location and size of each aneurysm, location, quality, intensity and duration of headaches, associated symptoms, triggering and alleviating factors, and precipitating events.

RESULTS

Forty-nine patients (60.5%) of 81 had chronic headaches before the diagnosis of unruptured intracranial aneurysm. Forty-four patients (89.8%) answered that their headaches were improved slightly (12 patients) or markedly (32 patients) (P <.05). The clinical pattern of the headache worsened in only 1 patient and did not change in 4 patients. When the surgical group (40 patients) and the coil embolization group (41 patients) were compared, there was no significant difference observed in outcome (P >.05).

CONCLUSION

Either by employing the technique of clipping or by coil embolization, treatment of unruptured intracranial aneurysms resulted in relief of headaches in majority of patients who had headaches pre-operatively.

摘要

目的

本研究的目的是确定为避免破裂风险而接受治疗的未破裂颅内动脉瘤患者头痛的发生率、特征及转归。

背景

未破裂颅内动脉瘤有多种临床表现。其中,慢性头痛是最常见的首发和/或伴随症状。

方法

在137例接受治疗的未破裂动脉瘤患者中,根据纳入标准排除30例后,我们收集了81例患者的数据。26例患者失访。我们通过病历回顾和电话调查收集数据。收集的信息包括对首发症状、每个动脉瘤的位置和大小、头痛的位置、性质、强度和持续时间、相关症状、诱发和缓解因素以及促发事件的分析。

结果

81例患者中有49例(60.5%)在未破裂颅内动脉瘤诊断之前有慢性头痛。44例患者(89.8%)回答他们的头痛有轻微改善(12例)或显著改善(32例)(P<.05)。只有1例患者头痛的临床模式恶化,4例患者头痛模式未改变。比较手术组(40例)和弹簧圈栓塞组(41例),转归方面未观察到显著差异(P>.05)。

结论

无论是采用夹闭技术还是弹簧圈栓塞术,治疗未破裂颅内动脉瘤均可使大多数术前有头痛的患者头痛得到缓解。

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