多粘菌素B对脂多糖引发的血清补体激活的抑制作用。
Inhibition of lipopolysaccharide-initiated activation of serum complement by polymyxin B.
作者信息
Morrison D C, Jacobs D M
出版信息
Infect Immun. 1976 Jan;13(1):298-301. doi: 10.1128/iai.13.1.298-301.1976.
Abstract
Treatment of bacterial lipopolysaccharides (endotoxins) isolated from Salmonella minnesota R595 or purified lipid A with the antibiotic polymyxin B has been demonstrated to abrogate the ability of these molecules to activate serum complement. The inhibition is a function of the ratio of polymyxin B to lipopolysaccharide.
摘要
已证明，用抗生素多粘菌素B处理从明尼苏达沙门氏菌R595分离出的细菌脂多糖（内毒素）或纯化的脂质A，可消除这些分子激活血清补体的能力。这种抑制作用是多粘菌素B与脂多糖比例的函数。
相似文献
1
Inhibition of lipopolysaccharide-initiated activation of serum complement by polymyxin B.多粘菌素B对脂多糖引发的血清补体激活的抑制作用。
Infect Immun. 1976 Jan;13(1):298-301. doi: 10.1128/iai.13.1.298-301.1976.
2
3
Mitogenic response of mouse spleen cells and gelation of limulus lysate by lipopolysaccharide of Yersinia pestis and evidence for neutralization of lipopolysaccharide by polymyxin B.鼠疫耶尔森菌脂多糖对小鼠脾细胞的促有丝分裂反应及鲎试剂凝胶化作用，以及多黏菌素B对脂多糖中和作用的证据。
Infect Immun. 1977 Nov;18(2):400-4. doi: 10.1128/iai.18.2.400-404.1977.
4
Polymyxin B sulfate modification of bacterial endotoxin: effects on the development of endotoxin shock in dogs.硫酸多粘菌素B对细菌内毒素的修饰：对犬内毒素休克发展的影响
Infect Immun. 1979 Mar;23(3):660-4. doi: 10.1128/iai.23.3.660-664.1979.
5
6
Action of polymyxin B on bacterial membranes. Binding capacities for polymyxin B of inner and outer membranes isolated from Salmonella typhimurium G30.
Arch Microbiol. 1976 Aug;109(1-2):51-8. doi: 10.1007/BF00425112.
7
New function for high density lipoproteins. Their participation in intravascular reactions of bacterial lipopolysaccharides.高密度脂蛋白的新功能。它们参与细菌脂多糖的血管内反应。
J Clin Invest. 1979 Nov;64(5):1516-24. doi: 10.1172/JCI109610.
8
Mechanism of polymyxin B-mediated lysis of lipopolysaccharide-treated erythrocytes.多粘菌素B介导脂多糖处理的红细胞裂解的机制。
Infect Immun. 1985 Jul;49(1):84-9. doi: 10.1128/iai.49.1.84-89.1985.
9
Polymyxin B suppresses the endotoxin inhibition of concanavalin a-mediated erythrocyte agglutination.多粘菌素B可抑制内毒素对伴刀豆球蛋白A介导的红细胞凝集反应的抑制作用。
Infect Immun. 1982 Feb;35(2):594-9. doi: 10.1128/iai.35.2.594-599.1982.
10
Lethal effect of complement and lysozyme on polymyxin-treated, serum-resistant gram-negative bacilli.补体和溶菌酶对经多粘菌素处理的血清抗性革兰氏阴性杆菌的致死作用。
J Infect Dis. 1979 Oct;140(4):581-9. doi: 10.1093/infdis/140.4.581.
引用本文的文献
1
Salmonella enterica Serovar Typhimurium Alters the Extracellular Proteome of Macrophages and Leads to the Production of Proinflammatory Exosomes.鼠伤寒沙门氏菌血清型改变巨噬细胞的细胞外蛋白质组，并导致促炎细胞外体的产生。
Infect Immun. 2018 Jan 22;86(2). doi: 10.1128/IAI.00386-17. Print 2018 Feb.
2
Eggshell membrane hydrolyzates activate NF-κB in vitro: possible implications for in vivo efficacy.蛋壳膜水解产物在体外激活核因子κB：对体内疗效的潜在影响
J Inflamm Res. 2015 Feb 9;8:49-57. doi: 10.2147/JIR.S78118. eCollection 2015.
3
SAOS-2 osteosarcoma cells bind fibroblasts via ICAM-1 and this is increased by tumour necrosis factor-α.骨肉瘤细胞系SAOS-2通过细胞间黏附分子-1（ICAM-1）与成纤维细胞结合，且肿瘤坏死因子-α可增强这种结合。
PLoS One. 2014 Jun 30;9(6):e101202. doi: 10.1371/journal.pone.0101202. eCollection 2014.
4
A clear and present danger: endogenous ligands of Toll-like receptors.明显而现实的危险： Toll 样受体的内源性配体。
Neuromolecular Med. 2010 Jun;12(2):149-63. doi: 10.1007/s12017-009-8094-x. Epub 2009 Oct 14.
5
Anthrax edema toxin induces maturation of dendritic cells and enhances chemotaxis towards macrophage inflammatory protein 3beta.炭疽水肿毒素可诱导树突状细胞成熟，并增强其对巨噬细胞炎性蛋白3β的趋化作用。
Infect Immun. 2009 May;77(5):2036-42. doi: 10.1128/IAI.01329-08. Epub 2009 Mar 9.
6
Lipopolysaccharide is a frequent and significant contaminant in microglia-activating factors.脂多糖是小胶质细胞激活因子中常见且重要的污染物。
Glia. 2008 Jan 1;56(1):16-26. doi: 10.1002/glia.20585.
7
Pharmacodynamics of polymyxin B against Pseudomonas aeruginosa.多粘菌素B对铜绿假单胞菌的药效学
Antimicrob Agents Chemother. 2005 Sep;49(9):3624-30. doi: 10.1128/AAC.49.9.3624-3630.2005.
8
Induction of monocyte expression of tumor necrosis factor alpha by the 30-kD alpha antigen of Mycobacterium tuberculosis and synergism with fibronectin.结核分枝杆菌30-kDα抗原诱导单核细胞表达肿瘤坏死因子α及其与纤连蛋白的协同作用。
J Clin Invest. 1996 Sep 1;98(5):1261-8. doi: 10.1172/JCI118910.
9
Binding of lysozyme to lipopolysaccharide suppresses tumor necrosis factor production in vivo.溶菌酶与脂多糖的结合可在体内抑制肿瘤坏死因子的产生。
Infect Immun. 1994 Apr;62(4):1171-5. doi: 10.1128/iai.62.4.1171-1175.1994.
10
Removal of endotoxin from antibody preparations for clinical use. Assessment of polymyxin-sepharose CNBr affinity chromatography.
Cell Biophys. 1994;24-25:9-14. doi: 10.1007/BF02789210.
本文引用的文献
1
Reduction of serum complement in rabbits after injection of endotoxin.注射内毒素后家兔血清补体的降低。
J Exp Med. 1962 Oct 1;116(4):477-90. doi: 10.1084/jem.116.4.477.
2
3
A new method for the extraction of R lipopolysaccharides.一种提取R脂多糖的新方法。
Eur J Biochem. 1969 Jun;9(2):245-9. doi: 10.1111/j.1432-1033.1969.tb00601.x.
4
5
Interaction of lipopolysaccharides and lipid A with complement.脂多糖和脂质A与补体的相互作用。
Eur J Biochem. 1971 Mar 1;19(1):143-52. doi: 10.1111/j.1432-1033.1971.tb01298.x.
6
Neutralization of the Shwartzman reactions by polymyxins B.多粘菌素B对施瓦茨曼反应的中和作用。
J Immunol. 1967 Sep;99(3):564-9.
7
Neutralization of the hemodynamic effects of endotoxin by polymyxin B.多粘菌素B对内毒素血流动力学效应的中和作用。
Surg Gynecol Obstet. 1974 May;138(5):755-9.
8
Endotoxin-induced intravascular coagulation: prevention with polymyxin B sulfate.内毒素诱导的血管内凝血：用硫酸多粘菌素B预防。
J Lab Clin Med. 1971 May;77(5):802-10.
9
Prevention by polymyxin B of endotoxin lethality in mice.多粘菌素B对小鼠内毒素致死性的预防作用。
J Bacteriol. 1967 Apr;93(4):1463-4. doi: 10.1128/jb.93.4.1463-1464.1967.
10
Neutralization of endotoxin toxicity in chick embryos by antibiotics.抗生素对鸡胚内毒素毒性的中和作用。
J Bacteriol. 1966 Oct;92(4):815-9. doi: 10.1128/jb.92.4.815-819.1966.
Zotero 插件