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自体块状骨移植与牙槽骨牵张成骨用于矫正垂直骨量不足的无牙颌牙槽嵴:一项针对人类的2至4年前瞻性研究。

Autogenous onlay bone grafts vs. alveolar distraction osteogenesis for the correction of vertically deficient edentulous ridges: a 2-4-year prospective study on humans.

作者信息

Chiapasco Matteo, Zaniboni Marco, Rimondini Lia

机构信息

Department of Medicine, Surgery, and Dentistry, Unit of Oral Surgery, San Paolo Hospital, University of Milan, Milan, Italy.

出版信息

Clin Oral Implants Res. 2007 Aug;18(4):432-40. doi: 10.1111/j.1600-0501.2007.01351.x. Epub 2007 May 14.

Abstract

OBJECTIVES

The purposes of this study were to compare: (a) autogenous bone grafts (ABG) and distraction osteogenesis (DO) for their ability in correcting vertically deficient mandibular ridges and their capability in maintaining over time the vertical bone gain obtained before and after implant placement; and (b) the survival and success rates of implants placed in the reconstructed or distracted areas.

MATERIAL AND METHODS

In a 2-year period (2001-2002), 17 patients presenting with vertically atrophied partially edentulous mandibles requiring implant-supported prosthetic rehabilitation, were included in this study. Patients were randomly assigned to two groups. Eight patients (group 1) were treated with ABG harvested from the mandibular ramus, while nine patients (group 2) were treated by means of DO. In group 1, patients received implants 4-5 months after the reconstructive procedure, while in group 2 implants were placed at the time of distraction device removal (approximately 3 months after the completion of distraction). A total of 19 endosseous implants were placed in group 1, and 21 implants were placed in group 2 patients. For both groups, after an additional 3-5-month period, prosthetic rehabilitation was started.

RESULTS

Bone resorption before implant placement was significantly higher in group 1 (P=0.01), while no statistically significant differences were found between the two groups as far as survival and success rates of implants and peri-implant bone resorption after the start of prosthetic loading were concerned.

CONCLUSION

The results suggested that: (a) both techniques may effectively improve the deficit of vertically resorbed edentulous ridges; (b) survival and success rates of implants placed in the reconstructed/distracted areas are consistent with those of implants placed in native bone.

摘要

目的

本研究的目的是比较:(a) 自体骨移植(ABG)和牵张成骨术(DO)在矫正垂直方向不足的下颌牙槽嵴方面的能力,以及在植入种植体前后随时间维持所获得的垂直骨增量的能力;(b) 种植体在重建或牵张区域的存留率和成功率。

材料与方法

在2年期间(2001 - 2002年),本研究纳入了17例患有垂直萎缩的部分牙列缺失下颌骨且需要种植体支持的修复治疗的患者。患者被随机分为两组。8例患者(第1组)接受取自下颌升支的自体骨移植治疗,而9例患者(第2组)接受牵张成骨术治疗。在第1组中,患者在重建手术后4 - 5个月接受种植体植入,而在第2组中,种植体在拆除牵张装置时(牵张完成后约3个月)植入。第1组共植入19枚骨内种植体,第2组患者植入21枚种植体。两组在额外的3 - 5个月后均开始进行修复治疗。

结果

第1组在种植体植入前的骨吸收明显更高(P = 0.01),而在种植体植入后开始进行修复加载时,就种植体的存留率和成功率以及种植体周围骨吸收而言,两组之间未发现统计学上的显著差异。

结论

结果表明:(a) 两种技术均可有效改善垂直吸收的无牙颌牙槽嵴的缺损情况;(b) 种植体在重建/牵张区域的存留率和成功率与在天然骨中植入的种植体一致。

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