Lakshminarayana Pradeep, Danson Sarah, Suvarna Kim, Hancock Barry
Department of Clinical Oncology, Weston Park Hospital, Whitham Road, Sheffield, S10 2SJ, UK.
J Med Case Rep. 2007 May 14;1:21. doi: 10.1186/1752-1947-1-21.
Malignant melanoma can metastasize to virtually any organ of the body. The aggressiveness is determined by the primary site, depth of dermal invasion, presence or absence of ulceration, lymphovascular infiltration and regional lymph node involvement. We report a case of a pregnant woman with a previous history of stage 3 melanoma who presented with cardiac metastasis and placental melanoma infiltration. A review of literature on cardiac and placental involvement of melanoma is also provided.
恶性黑色素瘤几乎可转移至身体的任何器官。其侵袭性由原发部位、真皮浸润深度、有无溃疡、淋巴管浸润及区域淋巴结受累情况决定。我们报告一例既往有3期黑色素瘤病史的孕妇，该患者出现心脏转移及胎盘黑色素瘤浸润。本文还对黑色素瘤累及心脏和胎盘的文献进行了综述。
