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Tilescope:用于高密度平铺微阵列数据的在线分析流程

Tilescope: online analysis pipeline for high-density tiling microarray data.

作者信息

Zhang Zhengdong D, Rozowsky Joel, Lam Hugo Y K, Du Jiang, Snyder Michael, Gerstein Mark

机构信息

Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA.

出版信息

Genome Biol. 2007;8(5):R81. doi: 10.1186/gb-2007-8-5-r81.

Abstract

We developed Tilescope, a fully integrated data processing pipeline for analyzing high-density tiling-array data http://tilescope.gersteinlab.org. In a completely automated fashion, Tilescope will normalize signals between channels and across arrays, combine replicate experiments, score each array element, and identify genomic features. The program is designed with a modular, three-tiered architecture, facilitating parallelism, and a graphic user-friendly interface, presenting results in an organized web page, downloadable for further analysis.

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/128a/1929149/fd7e6af941c4/gb-2007-8-5-r81-1.jpg

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