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[短期振动作用下大鼠组织抗氧化系统的年龄依赖性状态]

[Age-dependent status of the antioxidant system of rat tissues under the effect of short-term vibration].

作者信息

Makarov V G, Timofeeva V M

出版信息

Vopr Med Khim. 1991 Jul-Aug;37(4):48-51.

PMID:1750210
Abstract

Oxidation of low molecular thiols and ascorbic acid, alterations in superoxide dismutase, catalase, glutathione reductase and glucose-6-phosphate dehydrogenase activities were observed in erythrocytes and tissues of rats after short-term total vertical vibration. The rate of alterations found depended on the initial state of the antioxidative system components as well as on the vibration duration. The most pronounced impairments of the antioxidative system were detected in blood and nervous system of old animals in which the initial level of the antioxidative system functional activity was minimal.

摘要

在短期完全垂直振动后,观察到大鼠红细胞和组织中低分子硫醇和抗坏血酸的氧化、超氧化物歧化酶、过氧化氢酶、谷胱甘肽还原酶和葡萄糖-6-磷酸脱氢酶活性的改变。所发现的改变速率取决于抗氧化系统成分的初始状态以及振动持续时间。在老龄动物的血液和神经系统中检测到抗氧化系统最明显的损伤,这些动物抗氧化系统功能活性的初始水平最低。

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