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[儿童期经皮肺动脉狭窄球囊瓣膜成形术:早期血流动力学结果及长期多普勒超声心动图结果]

[Percutaneous balloon valvuloplasty of pulmonary stenosis in childhood: early hemodynamic results and long-term Doppler echocardiography results].

作者信息

Stein J I, Beitzke A, Suppan C

机构信息

Department für Pädiatrische Kardiologie, Universitätskinderklinik Graz, Universität Graz/Osterreich.

出版信息

Z Kardiol. 1991 Sep;80(9):549-53.

PMID:1750229
Abstract

Pulmonary balloon valvuloplasty was performed in 35 children aged 3 days to 18 years (mean 4.5 years). Balloon/annulus ratio was 1.21 +/- 0.12. There were 6 infants less than 1 year of age (including 1 newborn), 4 with dysplastic valves and 4 with postoperative restenosis. Systolic transvalvular gradient showed a decrease of 69 +/- 14% from 68 +/- 15 mm Hg before to 21 +/- 11 mm Hg after dilatation (p less than 0.0001), and right ventricular pressure/systemic pressure ratio decreased from 0.8 +/- 0.29 to 0.4 +/- 0.15 (p less than 0.0001). Follow-up studies were performed in all patients up to 5 years (2.5 +/- 1.3 years) after dilatation. In 63% (22/35) follow-up period was more than 2 years (3.5 +/- 0.95 years). Doppler derived gradient had further decreased to 16 +/- 11 mm Hg (n.s.). Results in the 6 infants showed an immediate gradient relief of 71 +/- 11% from 85 +/- 4 mm Hg to 25 +/- 10 mm Hg (p less than 0.0001) with a further decrease to 20 +/- 10 mm Hg at follow-up. There were two early complications which had to be treated (tachycardia in WPW-syndrome, femoral vein dissection), no late complications were seen. The good immediate results and high persistent long-term success rate confirm balloon pulmonary valvuloplasty being the treatment of first choice for all patients in childhood.

摘要

对35名年龄在3天至18岁(平均4.5岁)的儿童进行了肺动脉球囊瓣膜成形术。球囊/瓣环比率为1.21±0.12。有6名1岁以下的婴儿(包括1名新生儿),4名瓣膜发育不良,4名术后再狭窄。收缩期跨瓣压差显示从扩张前的68±15mmHg降至扩张后的21±11mmHg,下降了69±14%(p<0.0001),右心室压力/体循环压力比率从0.8±0.29降至0.4±0.15(p<0.0001)。对所有患者在扩张后长达5年(2.5±1.3年)进行了随访研究。63%(22/35)的随访期超过2年(3.5±0.95年)。经多普勒测定的压差进一步降至16±11mmHg(无统计学意义)。6名婴儿的结果显示,压差立即从85±4mmHg降至25±10mmHg,缓解了71±11%(p<0.0001),随访时进一步降至20±10mmHg。有2例早期并发症需要治疗(预激综合征中的心动过速、股静脉夹层),未见晚期并发症。良好的即刻效果和较高的长期持续成功率证实了球囊肺动脉瓣膜成形术是儿童所有患者的首选治疗方法。

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