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[出血后低血容量肠内纠正机制]

[Mechanisms of enteral correction of posthemorrhagic hypovolemia].

作者信息

Koval'skaia K S

出版信息

Vestn Akad Med Nauk SSSR. 1991(9):42-6.

PMID:1750244
Abstract

It has been demonstrated in chronic experiments that after hemorrhage liquid absorption from the small intestine does not interfere with the process of its supply from the interstice. Totally both these processes considerably enhance the degree of autohemodilution. Infusion of the electrolyte monomer solution to the duodenum of the dogs which suffered hemorrhage (20-50 ml/kg bw) ensure, during the preserving of absorption function, a rapid and stable growth of the circulating plasma volume, proteins, sodium and potassium, being an effective means of steady replenishment of posthemorrhagic hypovolemia. Reduction of water-retaining plasma components discovered in the experiments attests to the participation of the digestive organs in formation of the basic volemia substrate water-protein-electrolyte in volemic homeostasis maintenance.

摘要

慢性实验表明,出血后小肠对液体的吸收并不干扰其从组织间隙获得供应的过程。这两个过程总体上都显著提高了自身血液稀释的程度。向出血(20 - 50毫升/千克体重)的狗的十二指肠输注电解质单体溶液,在保持吸收功能的过程中,可确保循环血浆量、蛋白质、钠和钾快速稳定增长,是稳定补充出血后低血容量的有效手段。实验中发现的保水性血浆成分的减少证明了消化器官参与了维持容量稳态时基本容量底物水 - 蛋白质 - 电解质的形成。

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