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硅水凝胶隐形眼镜的动态接触角分析。

Dynamic contact angle analysis of silicone hydrogel contact lenses.

机构信息

Eurolens Research, Faculty of Life Sciences, The University of Manchester, Manchester, UK.

出版信息

J Biomater Appl. 2011 Jul;26(1):85-99. doi: 10.1177/0885328210363505. Epub 2010 Mar 10.

Abstract

Contact angle measurements are used to infer the clinical wetting characteristics of contact lenses. Such characterization has become more commonplace since the introduction of silicone hydrogel contact lens materials, which have been associated with reduced in vivo wetting due to the inclusion of siloxane-containing components. Using consistent methodology and a single investigator, advancing and receding contact angles were measured for 11 commercially available silicone hydrogel contact lens types with a dynamic captive bubble technique employing customized, fully automated image analysis. Advancing contact angles were found to range between 20° and 72° with the lenses falling into six statistically discrete groupings. Receding contact angles fell within a narrower range, between 17° and 22°, with the lenses segregated into three groups. The relationship between these laboratory measurements and the clinical performance of the lenses requires further investigation.

摘要

接触角测量用于推断隐形眼镜的临床润湿特性。自从硅水凝胶隐形眼镜材料问世以来,这种特性的描述变得更加普遍,因为这些材料中含有硅氧烷成分,与体内湿润度降低有关。使用一致的方法和单一的调查人员,采用定制的全自动图像分析技术,使用动态俘获气泡技术,对 11 种市售硅水凝胶隐形眼镜类型的前进和后退接触角进行了测量。前进接触角的范围在 20°至 72°之间,镜片可分为六个统计学上离散的组。后退接触角的范围较窄,在 17°至 22°之间,镜片分为三组。这些实验室测量结果与镜片的临床性能之间的关系需要进一步研究。

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