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[生物阿尔卡明植入物的皮肤不良反应]

[Cutaneous adverse reaction to Bio-Alcamid implant].

作者信息

Gómez-de la Fuente E, Alvarez-Fernández J G, Pinedo F, Naz E, Gamo R, Vicente-Martín F J, López-Estebaranz J L

机构信息

Unidades de Dermatología, Fundación Hospital Alcorcón, Madrid, España.

出版信息

Actas Dermosifiliogr. 2007 May;98(4):271-5.

Abstract

In the last years new and numerous materials for the correction of defects and wrinkles have been developed. One of these materials is Bio-Alcamid, a non reabsorbable gel polymer constituted by meshes of poly-alkyl-imide, without known adverse effects. We report a 34-year-old woman that had Bio-Alcamid implants for acne scars and several months after presented nodular lesions together with a painful inflammatory nodule. The nodule was drained and culture of the purulent material yielded Streptococcus viridans. A cytology and a cellular block of that material showed a granulomatous inflammatory reaction together with a foreign body. The different types of reactions to implants and their pathogenic mechanism are discussed. It is important to know these possible reactions to filler materials given their increasing use and the potential medico-legal consequences.

摘要

在过去几年中,已开发出多种用于修复缺陷和皱纹的新型材料。其中一种材料是Bio-Alcamid,它是一种不可吸收的凝胶聚合物,由聚烷基酰亚胺网构成,尚无已知的不良反应。我们报告了一名34岁女性,她接受了Bio-Alcamid植入物治疗痤疮疤痕,几个月后出现结节性病变以及一个疼痛的炎性结节。该结节进行了引流,脓性物质培养出草绿色链球菌。对该物质进行的细胞学和细胞块检查显示出肉芽肿性炎症反应以及异物。本文讨论了对植入物的不同类型反应及其致病机制。鉴于填充材料的使用日益增加以及潜在的医疗法律后果,了解这些对填充材料可能的反应非常重要。

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