• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

干细胞及其微环境:一种不可分割的关系。

Stem cells and their niche: an inseparable relationship.

作者信息

Xie Ting, Li Linheng

机构信息

Stowers Institute for Medical Research, 1000 East 50th Street, Kansas City, MO 64110, USA.

出版信息

Development. 2007 Jun;134(11):2001-6. doi: 10.1242/dev.002022.

DOI:10.1242/dev.002022
PMID:17507401
Abstract

A recent Keystone symposium on 'Stem Cell Interactions with their Microenvironmental Niche' was organized by David T. Scadden and Allan C. Spradling. The meeting was held in conjunction with another Keystone symposium, 'Stem Cells and Cancer', at Keystone, Colorado. Among the work that was presented at this meeting, scientists presented data that advances our understanding of the contribution that the niche makes to stem cell maintenance. Novel types of stem cells and niches were also reported and new findings that clarify our understanding of the molecular mechanisms that regulate and maintain stem cells were presented.

摘要

最近,由大卫·T·斯卡登和艾伦·C·斯普拉德林组织了一场关于“干细胞与其微环境生态位的相互作用”的基斯通研讨会。该会议与另一场在科罗拉多州基斯通举行的基斯通研讨会“干细胞与癌症”联合举办。在本次会议上展示的研究成果中,科学家们展示的数据推动了我们对生态位对干细胞维持所做贡献的理解。还报告了新型干细胞及生态位,并展示了有助于阐明我们对调控和维持干细胞分子机制理解的新发现。

相似文献

1
Stem cells and their niche: an inseparable relationship.干细胞及其微环境:一种不可分割的关系。
Development. 2007 Jun;134(11):2001-6. doi: 10.1242/dev.002022.
2
Understanding hematopoietic stem-cell microenvironments.了解造血干细胞微环境。
Trends Biochem Sci. 2006 Oct;31(10):589-95. doi: 10.1016/j.tibs.2006.08.001. Epub 2006 Sep 5.
3
Haematopoietic stem cells niches: interrelations between structure and function.造血干细胞龛:结构与功能之间的相互关系。
Transfus Apher Sci. 2008 Jun;38(3):261-8. doi: 10.1016/j.transci.2008.04.006. Epub 2008 May 16.
4
Evolving concepts on the microenvironmental niche for hematopoietic stem cells.造血干细胞微环境生态位的概念演变
Curr Opin Hematol. 2008 Jul;15(4):301-6. doi: 10.1097/MOH.0b013e328303e14c.
5
Extramedullary hematopoiesis: a new look at the underlying stem cell niche, theories of development, and occurrence in animals.髓外造血:对基础造血干细胞龛、发育理论以及动物发生的新认识。
Vet Pathol. 2012 May;49(3):508-23. doi: 10.1177/0300985811432344. Epub 2012 Jan 18.
6
Haematopoietic stem cell niche in Drosophila.果蝇中的造血干细胞微环境
Bioessays. 2007 Aug;29(8):713-6. doi: 10.1002/bies.20613.
7
Hematopoietic stem cells: generation and self-renewal.造血干细胞:生成与自我更新。
Cell Death Differ. 2007 Nov;14(11):1851-9. doi: 10.1038/sj.cdd.4402225. Epub 2007 Sep 7.
8
Beyond angiogenesis: the role of endothelium in the bone marrow vascular niche.超越血管生成:内皮细胞在骨髓血管微环境中的作用
Transl Res. 2008 Jan;151(1):1-9. doi: 10.1016/j.trsl.2007.09.003. Epub 2007 Oct 4.
9
Insights into signaling and function of hematopoietic stem cells at the single-cell level.单细胞水平下造血干细胞信号传导与功能的见解
Curr Opin Hematol. 2009 Jul;16(4):255-8. doi: 10.1097/MOH.0b013e32832c6705.
10
[Role of osteoblasts in the hematopoietic microenvironment of bone marrow and regulatory pathways and mechanisms].[成骨细胞在骨髓造血微环境中的作用及调控途径和机制]
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2007 May;21(5):517-22.

引用本文的文献

1
Nuclear compression-mediated DNA damage drives ATR-dependent Lamin expression and mouse ESC differentiation.核压缩介导的DNA损伤驱动ATR依赖的核纤层蛋白表达和小鼠胚胎干细胞分化。
Nucleic Acids Res. 2025 Sep 5;53(17). doi: 10.1093/nar/gkaf852.
2
A regulatory loop of JAK/STAT signalling and its downstream targets represses cell fate conversion and maintains male germline stem cell niche homeostasis.JAK/STAT 信号通路及其下游靶标的调控环路抑制细胞命运转变并维持雄性生殖干细胞龛的稳态。
Cell Prolif. 2024 Oct;57(10):e13648. doi: 10.1111/cpr.13648. Epub 2024 Jul 10.
3
Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Rescue Testicular Aging.
人脐带间充质干细胞来源的外泌体可挽救睾丸衰老。
Biomedicines. 2024 Jan 3;12(1):98. doi: 10.3390/biomedicines12010098.
4
Expression of Stemness Markers in the Cervical Smear of Patients with Cervical Insufficiency.在宫颈机能不全患者的宫颈涂片上表达干性标志物。
Cells. 2023 Apr 18;12(8):1183. doi: 10.3390/cells12081183.
5
A concise review on miRNAs as regulators of colon cancer stem cells and associated signalling pathways.微小 RNA 作为结肠癌干细胞及其相关信号通路调控因子的简要综述。
Clin Transl Oncol. 2023 Dec;25(12):3345-3356. doi: 10.1007/s12094-023-03200-x. Epub 2023 Apr 22.
6
First observations of ovary regeneration in an amphipod, Krøyer, 1842.首次观察到的一种端足目动物(Krøyer, 1842)的卵巢再生现象。
PeerJ. 2022 Mar 10;10:e12950. doi: 10.7717/peerj.12950. eCollection 2022.
7
Estrogen Receptor Functions and Pathways at the Vascular Immune Interface.血管免疫界面处的雌激素受体功能与信号通路
Int J Mol Sci. 2021 Apr 20;22(8):4254. doi: 10.3390/ijms22084254.
8
Scaffold-based 3D cellular models mimicking the heterogeneity of osteosarcoma stem cell niche.基于支架的 3D 细胞模型模拟骨肉瘤干细胞龛的异质性。
Sci Rep. 2020 Dec 18;10(1):22294. doi: 10.1038/s41598-020-79448-y.
9
GFRα 1-2-3-4 co-receptors for RET Are co-expressed in Pituitary Stem Cells but Individually Retained in Some Adenopituitary Cells.RET的GFRα 1-2-3-4共受体在垂体干细胞中共同表达,但在一些腺垂体细胞中单独保留。
Front Endocrinol (Lausanne). 2020 Sep 24;11:631. doi: 10.3389/fendo.2020.00631. eCollection 2020.
10
The Cross Talk between Cancer Stem Cells/Cancer Initiating Cells and Tumor Microenvironment: The Missing Piece of the Puzzle for the Efficient Targeting of these Cells with Immunotherapy.癌症干细胞/癌症起始细胞与肿瘤微环境之间的相互作用:免疫疗法有效靶向这些细胞的关键缺失环节。
Cancer Microenviron. 2019 Dec;12(2-3):133-148. doi: 10.1007/s12307-019-00233-1. Epub 2019 Nov 22.