Meyer Walter J, Blakeney Patricia, Thomas Christopher R, Russell William, Robert Rhonda S, Holzer Charles E
General Clinical Research Center, University of Texas Medical Branch at Galveston, TX 77555-0189, USA.
Psychosom Med. 2007 May;69(4):377-82. doi: 10.1097/PSY.0b013e3180600a2e. Epub 2007 May 17.
To determine the prevalence of major psychiatric illness in a group of young adults who suffered significant burn injury as children.
A total of 101 persons (58 males, 43 females), aged 21 +/- 2.6 years, 14.0 +/- 5.4 years postburn of 54% +/- 20% total body surface area, were assessed for serious past and present mental illness by using a Structured Clinical Interview (SCID) for Diagnostic and Statistical Manual of Mental Disorders, 4th Edition (DSM-IV) Axis I diagnoses.
The SCID findings demonstrated that the prevalence of any Axis I major mental illness was 45.5% for the past month (current) and 59.4% for lifetime. These rates of overall disorder and the rates for most specific disorders were significantly higher than those found in the US population of comparable age. Logistic regression was used to examine demographic and burn characteristics as predictors of current and lifetime psychiatric disorder within the burn survivor sample. The female gender was significantly associated with higher rates of any current disorder. Other demographic and burn characteristics were not significantly related to the overall prevalence of current or lifetime disorder. Only a small number of those with disorders reported any current mental health treatment.
Significant burn injury as a child leads to an increased risk of developing a major mental illness. Young adults who suffered major burn injury as children should be screened for these illnesses to initiate appropriate treatment.
确定一组童年时期遭受严重烧伤的年轻成年人中主要精神疾病的患病率。
共有101人（58名男性，43名女性），年龄21±2.6岁，烧伤后14.0±5.4年，烧伤面积占体表面积的54%±20%，通过使用《精神疾病诊断与统计手册》第4版（DSM-IV）轴I诊断的结构化临床访谈（SCID）对过去和现在的严重精神疾病进行评估。
SCID的结果表明，过去一个月（当前）任何轴I主要精神疾病的患病率为45.5%，终生患病率为59.4%。这些总体疾病发生率以及大多数特定疾病的发生率显著高于美国同龄人群中的发生率。使用逻辑回归分析来检验人口统计学和烧伤特征，作为烧伤幸存者样本中当前和终生精神疾病的预测因素。女性性别与任何当前疾病的较高发生率显著相关。其他人口统计学和烧伤特征与当前或终生疾病的总体患病率没有显著关系。只有少数患有疾病的人报告了当前的任何心理健康治疗。
儿童时期严重烧伤会增加患主要精神疾病的风险。童年时期遭受严重烧伤的年轻成年人应接受这些疾病的筛查，以便开始适当的治疗。
