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良性直肠阴道瘘:个人系列病例的治疗与结果

Benign rectovaginal fistulas: management and results of a personal series.

作者信息

Devesa J M, Devesa M, Velasco G R, Vicente R, García-Moreno F, Rey A, López-Hervás P, Die J, Molina J M

机构信息

Coloproctology Unit, Department of General Surgery, University Hospital Ramón y Cajal, Area Sanitaria 4, 28034 Madrid, Spain.

出版信息

Tech Coloproctol. 2007 Jun;11(2):128-34. doi: 10.1007/s10151-007-0342-1. Epub 2007 May 25.

Abstract

BACKGROUND

Treatment of benign rectovaginal fistula has a high failure rate and entails difficult decisions. The purpose of this retrospective study was to clarify the concepts which may improve its management.

METHODS

Between 1983 and 2004, 46 consecutive women of median age 41 years were treated by the same surgeon. Etiology of simple fistulas was iatrogenic (n=6), obstetric (n=4) and septic (n=3). Complex fistulas were due to inflammatory bowel diseases (IBD) (n=18, 11 pouchvaginal) or were iatrogenic (n=9), actinic (n=5) or septic (n=1). Surgical techniques included endorectal or vaginal advancement flaps, fistulectomy and sphincteroplasty, vaginal/rectal closure and epiploplasty, restorative proctectomy and restorative proctocolectomy. In 20 patients, a diverting stoma was performed as a single procedure or concomitant to the curative attempt.

RESULTS

Overall, 33 of the 39 fistulas (85%) treated for cure healed, including all simple fistulas and 20 complex fistulas (8 iatrogenic, 3 actinic, 2 ulcerative colitis without restorative proctocolectomy; 5 pouch vaginal; 1 septic; 1 Crohn's disease) (p=0.009). The first operation for the fistula was curative in 20 of 39 fistulas, including 10 of 13 simple and 10 of 26 complex fistulas (p=0.023). There was no significant age difference between cured and not-cured patients.

CONCLUSIONS

Simple versus complex fistulas is the most determinant factor for healing. In IBD fistulas, ulcerative colitis shows better prognosis than Crohn's disease. For complex fistulas, a temporary diverting stoma seems necessary.

摘要

背景

良性直肠阴道瘘的治疗失败率高,且需要做出艰难的决策。本回顾性研究的目的是明确可能改善其治疗的相关概念。

方法

1983年至2004年间,同一位外科医生连续治疗了46名年龄中位数为41岁的女性。单纯性瘘的病因包括医源性(n = 6)、产科(n = 4)和感染性(n = 3)。复杂性瘘是由炎症性肠病(IBD)引起的(n = 18,其中11例为贮袋阴道瘘),或医源性(n = 9)、光化性(n = 5)或感染性(n = 1)。手术技术包括直肠内或阴道推进皮瓣、瘘管切除术和括约肌成形术、阴道/直肠闭合术和网膜成形术、保留性直肠切除术和保留性直肠结肠切除术。20例患者进行了转流造口术,作为单一手术或与根治性尝试同时进行。

结果

总体而言,39例接受根治性治疗的瘘中有33例(85%)愈合,包括所有单纯性瘘和20例复杂性瘘(8例医源性、3例光化性、2例未行保留性直肠结肠切除术的溃疡性结肠炎;5例贮袋阴道瘘;1例感染性;1例克罗恩病)(p = 0.009)。39例瘘中首次手术即治愈的有20例,包括13例单纯性瘘中的10例和复杂瘘中的10例(26例中的10例)(p = 0.023)。治愈和未治愈患者之间年龄无显著差异。

结论

单纯性瘘与复杂性瘘是愈合的最决定性因素。在IBD瘘中,溃疡性结肠炎的预后比克罗恩病好。对于复杂性瘘,似乎需要临时转流造口术。

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