Cannizzo Francesca T, Eraso Elena, Ezkurra Pilar A, Villar-Vidal María, Bollo Enrico, Castellá Gemma, Cabañes F Javier, Vidotto Valerio, Quindós Guillermo
Laboratorio de Micología Médica, Departamento de Inmunología, Microbiología y Parasitología, Facultad de Medicina y Odontología, Universidad del País Vasco-Euskal Herriko Unibertsitatea, Bilbao, Spain.
Med Mycol. 2007 Jun;45(4):357-61. doi: 10.1080/13693780701225767.
Malassezia pachydermatis fungemia has been reported in patients receiving parenteral nutrition. Biofilm formation on catheters may be related to the pathogenesis of this mycosis. We investigated the biofilm-forming ability of 12 M. pachydermatis strains using a metabolic activity plate-based model and electronic microscopic evaluation of catheter surfaces. All M. pachydermatis strains developed biofilms but biofilm formation showed variability among the different strains unrelated to their clinical origin. This study demonstrates the ability of M. pachydermatis to adhere to and form biofilms on the surfaces of different materials, such as polystyrene and polyurethane.
在接受肠外营养的患者中已报告有厚皮马拉色菌血症。导管上生物膜的形成可能与这种真菌病的发病机制有关。我们使用基于代谢活性平板的模型和导管表面的电子显微镜评估，研究了12株厚皮马拉色菌菌株的生物膜形成能力。所有厚皮马拉色菌菌株均形成了生物膜，但生物膜形成在不同菌株之间存在差异，且与它们的临床来源无关。本研究证明了厚皮马拉色菌能够在不同材料（如聚苯乙烯和聚氨酯）表面黏附并形成生物膜。
