引起菌血症的新兴关注酵母菌种。
spp. Yeasts of Emerging Concern in Fungemia.
作者信息
Rhimi Wafa, Theelen Bart, Boekhout Teun, Otranto Domenico, Cafarchia Claudia
机构信息
Dipartimento di Medicina Veterinaria, Università degli Studi "Aldo Moro", Bari, Italy.
Yeast Research, Westerdijk Fungal Biodiversity Institute, Utrecht, Netherlands.
出版信息
Front Cell Infect Microbiol. 2020 Jul 28;10:370. doi: 10.3389/fcimb.2020.00370. eCollection 2020.
Abstract
spp. are lipid-dependent yeasts, inhabiting the skin and mucosa of humans and animals. They are involved in a variety of skin disorders in humans and animals and may cause bloodstream infections in severely immunocompromised patients. Despite a tremendous increase in scientific knowledge of these yeasts during the last two decades, the epidemiology of spp. related to fungemia remains largely underestimated most likely due to the difficulty in the isolation of these yeasts species due to their lipid-dependence. This review summarizes and discusses the most recent literature on spp. infection and fungemia, its occurrence, pathogenicity mechanisms, diagnostic methods, susceptibility testing and therapeutic approaches.
摘要
某些种是脂质依赖性酵母，寄居于人和动物的皮肤及黏膜。它们与人和动物的多种皮肤疾病有关，并且可能在严重免疫功能低下的患者中引起血流感染。尽管在过去二十年里对这些酵母的科学认识有了巨大增长，但由于这些酵母具有脂质依赖性，分离困难，与真菌血症相关的某些种的流行病学很可能仍被大大低估。本综述总结并讨论了关于某些种感染和真菌血症的最新文献，包括其发生情况、致病机制、诊断方法、药敏试验及治疗方法。
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