Uy Harvey Siy, Tuano Prospero Ma C
Sentro Oftalmologico Jose Rizal, Department of Ophthalmology, University of the Philippines, Philippine General Hospital, Manila, Philippines.
Orbit. 2007 Mar;26(1):33-7. doi: 10.1080/01676830600671474.
To report the clinical features, etiology, management practices, and outcomes of preseptal (PC) and orbital cellulitis (OC) in a developing country.
The charts of all patients with PC and OC at the Philippine General Hospital from 1990 to 1995 were reviewed and the following data retrieved: age, gender, manner of presentation, causative agent, treatment, and outcomes.
Of 91 patients, 56 (62%) were diagnosed with PC and 35 (38%) with OC. The mean age at presentation was 12.6 +/- 17.0 years and 17.1 +/- 18.6 years, respectively. No sex predilection was observed. Ophthalmoplegia, chemosis, pain, proptosis, and blurred vision were associated with OC. Eyelid infection was the most common antecedent factor and was present in 15 (27%) PC patients and 13 (37%) OC patients. Staphylococcus was the most frequent causative organism. Intravenous antibiotics were administered to 35 (62%) PC patients and all patients with OC. Surgical intervention was performed in 15 (27%) PC patients and 22 (63%) OC patients. None of the PC patients developed permanent sequelae. Seventeen (49%) OC patients developed serious complications such as: visual loss (29%), neurological deficits (17%), and mortality (3%).
In developing countries, eyelid infection may be the most important predisposing factor for periocular infection. Staphylococcus is the predominant causative agent. OC can be associated with serious complications. Aggressive management of OC may improve patient outcomes.
报告一个发展中国家眶隔前蜂窝织炎(PC)和眼眶蜂窝织炎(OC)的临床特征、病因、治疗方法及治疗结果。
回顾了1990年至1995年在菲律宾总医院所有PC和OC患者的病历,并收集了以下数据:年龄、性别、临床表现方式、病原体、治疗方法及治疗结果。
91例患者中,56例(62%)被诊断为PC,35例(38%)被诊断为OC。就诊时的平均年龄分别为12.6±17.0岁和17.1±18.6岁。未观察到性别差异。眼肌麻痹、结膜水肿、疼痛、眼球突出和视力模糊与OC相关。眼睑感染是最常见的前驱因素,在15例(27%)PC患者和13例(37%)OC患者中出现。葡萄球菌是最常见的病原体。35例(62%)PC患者和所有OC患者均接受了静脉抗生素治疗。15例(27%)PC患者和22例(63%)OC患者接受了手术干预。PC患者均未出现永久性后遗症。17例(49%)OC患者出现了严重并发症,如视力丧失(29%)、神经功能缺损(17%)和死亡(3%)。
在发展中国家,眼睑感染可能是眼周感染最重要的易感因素。葡萄球菌是主要病原体。OC可能与严重并发症相关。积极治疗OC可能改善患者预后。