Mesana T, Mitsui N, Trinkl J, Demunck J L, Havlik P, Montiès J R
Laboratoire Recherches Chirurgicales, Faculté de Médecine, Université Aix-Marseille II, France.
ASAIO Trans. 1991 Jul-Sep;37(3):M166-8.
The authors' laboratory is developing a device for heterotopic left ventricular assistance. It consists of a titanium Wankel-type rotary pump, driven by an hermetically sealed electric motor. In our animal experiments, the motor-pump unit was implanted in the thoracic wall. The pump was connected to the left heart chambers by left atrial cannulation, and to the descending aorta. The motor was connected to the power and control unit by an electric wire through the skin. In this report, the authors describe the first significant animal survival with this system. Laboratory results were encouraging for hemolysis. The pump failed at 13 days due to a deposit of fibrin and blood cells in the gear housing. This problem was not surprising since similar events have been encountered with centrifugal devices. However, further design improvements should allow longer animal survival and clinical application.
作者所在实验室正在研发一种用于异位左心室辅助的装置。它由一个钛制汪克尔型旋转泵组成，由一个密封的电动马达驱动。在我们的动物实验中，电动泵单元被植入胸壁。泵通过左心房插管与左心腔相连，并与降主动脉相连。马达通过一根电线穿过皮肤与动力和控制单元相连。在本报告中，作者描述了使用该系统首次实现的动物显著存活情况。实验室结果对于溶血情况令人鼓舞。泵在13天时因齿轮箱中出现纤维蛋白和血细胞沉积而失效。这个问题并不意外，因为在离心式装置中也曾遇到过类似情况。然而，进一步的设计改进应该能够实现动物更长时间的存活以及临床应用。
