Tomczak M M, Slocik J M, Stone M O, Naik R R
Materials and Manufacturing Directorate, Air Force Research Laboratory, Wright-Patterson AFB, OH 45433, USA.
Biochem Soc Trans. 2007 Jun;35(Pt 3):512-5. doi: 10.1042/BST0350512.
Nature is an exquisite designer of inorganic materials using biomolecules as templates. Diatoms create intricate silica wall structures with fine features using the protein family of silaffins as templates. Marine sponges create silica spicules also using proteins, termed silicateins. In recent years, our group and others have used biomolecules as templates for the deposition of inorganic materials. In contrast with the traditional materials science approach, which requires high heat, extreme pH and non-aqueous solutions, the bio-based approaches allow the reactions to proceed usually at near ambient conditions. Additionally, the biological templates allow for the control of the inorganic nanoparticle morphology. The use of peptides and biomolecules for templating and assembling inorganics will be discussed here.
大自然是一位精巧的无机材料设计师，它利用生物分子作为模板。硅藻以硅成蛋白家族为模板，创造出具有精细特征的复杂二氧化硅壁结构。海洋海绵也利用被称为硅酸酶的蛋白质来制造二氧化硅骨针。近年来，我们团队和其他一些团队已将生物分子用作无机材料沉积的模板。与传统材料科学方法（需要高温、极端pH值和非水溶液）不同，基于生物的方法通常允许反应在接近环境条件下进行。此外，生物模板能够控制无机纳米颗粒的形态。本文将讨论使用肽和生物分子进行无机材料的模板化和组装。
