Feldheim Daniel L, Eaton Bruce E
Department of Chemistry and Biochemistry, University of Colorado, Boulder, CO 80309, USA.
ACS Nano. 2007 Oct;1(3):154-9. doi: 10.1021/nn7002019.
Biopolymers in the biosphere are well known to mediate the formation of a wide array of inorganic materials, such as bone, shells, lenses, and magnetic particles to name a few. Recently, in vitro experiments with biopolymers such as peptides, RNA, and DNA have shown that templating by these macromolecules can yield a variety of materials under mild reaction conditions. The primary sequence of the biopolymer can be viewed as a proteomic or genomic signature for the templating of an inorganic material from defined metal precursors and reaction conditions. Together with the rapid advances in inorganic particle synthesis by other combinatorial methods, these bioinspired in vitro materials experiments may provide additional insights into possible inorganic materials yet to be discovered and subsequently synthesized by conventional methods. Some of the concepts important to understanding the crystallization phenomena occurring during biopolymer mediation are discussed. A simple kinetic model is provided in the context of known biopolymer-mediated inorganic crystallizations.
众所周知，生物圈中的生物聚合物可介导多种无机材料的形成，如骨骼、贝壳、晶状体和磁性颗粒等。最近，对肽、RNA和DNA等生物聚合物进行的体外实验表明，在温和的反应条件下，这些大分子的模板作用可以产生多种材料。生物聚合物的一级序列可被视为一种蛋白质组学或基因组特征，用于在特定的金属前体和反应条件下模板化无机材料。随着通过其他组合方法进行无机颗粒合成的迅速发展，这些受生物启发的体外材料实验可能会为尚未被发现且随后无法通过传统方法合成的潜在无机材料提供更多见解。本文讨论了一些对于理解生物聚合物介导过程中发生的结晶现象至关重要的概念。在已知的生物聚合物介导的无机结晶背景下提供了一个简单的动力学模型。
