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使用匹配追踪法提取的灵长类动物慢序列多焦视网膜电图的振荡电位。

Oscillatory potentials of the slow-sequence multifocal ERG in primates extracted using the Matching Pursuit method.

作者信息

Zhou Wei, Rangaswamy Nalini, Ktonas Periklis, Frishman Laura J

机构信息

College of Optometry, University of Houston, Houston, TX, USA.

出版信息

Vision Res. 2007 Jul;47(15):2021-36. doi: 10.1016/j.visres.2007.03.021. Epub 2007 May 23.

Abstract

This study used the Matching Pursuit (MP) method, a time-frequency analysis, to identify and characterize oscillatory potentials (OPs) in the primate electroretinogram (ERG). When the slow-sequence mfERG from the macular region of the retina was matched with Gabor functions, OPs were identified in two distinct bands: a high-frequency band peaking around 150 Hz that contributes to early OPs, and a low-frequency band peaking around 80 Hz that contributes to both early and late OPs. Pharmacological blockade and experimental glaucoma studies showed that the high-frequency OPs depend upon sodium-dependent spiking activity of retinal ganglion cells, whereas the low-frequency OPs depend primarily upon non-spiking activity of amacrine cells, and more distal retinal activity.

摘要

本研究采用匹配追踪(MP)方法,一种时频分析方法,来识别和表征灵长类动物视网膜电图(ERG)中的振荡电位(OPs)。当将来自视网膜黄斑区域的慢序列多焦视网膜电图(mfERG)与伽柏函数进行匹配时,在两个不同的频段中识别出了OPs:一个高频频段在150Hz左右达到峰值,它对早期OPs有贡献;一个低频频段在80Hz左右达到峰值,它对早期和晚期OPs均有贡献。药理学阻断和实验性青光眼研究表明,高频OPs依赖于视网膜神经节细胞的钠依赖性放电活动,而低频OPs主要依赖于无长突细胞的非放电活动以及更远端的视网膜活动。

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