Islamoglu Fatih, Apaydin Anil Ziya, Posacioglu Hakan, Calkavur Tanzer, Yagdi Tahir, Atay Yüksel
Department of Cardiovascular Surgery, Ege University Medical Faculty, 35100 Izmir, Turkey.
Ann Vasc Surg. 2007 Jul;21(4):423-32. doi: 10.1016/j.avsg.2006.12.005. Epub 2007 May 18.
The purpose of this study was to determine the effects of hiatal and thoracic clamping on postoperative outcome and morbidity and factors affecting mortality and morbidity. The records of 102 patients who had undergone ruptured abdominal aortic aneurysm repair between 1993 and 2005 were evaluated retrospectively. Hiatal clamping and thoracic clamping were performed in 72 patients and 30 patients, respectively. Postoperative complications and survival were evaluated comparatively between the two groups by univariate and multivariate statistical analyses. Overall mortality and hospital mortality rates were 63 (61.8%) and 24 (23.5%) patients, respectively; and there was no difference between the two groups. Postoperative respiratory complications, gastrointestinal complications, and blood requirement were higher in the thoracic clamping group. Preoperative shock and renal ischemia time (>30 min) were found to be significant predictors of hospital mortality. Postoperative renal failure was the only independent postoperative predictor of mortality. In the follow-up period, cardiac event was an independent predictor of late mortality. If hospital mortalities were excluded, 5-year and 10-year cumulative survivals were 57.82 +/- 5.85% and 38.16 +/- 6.97%, respectively. Cross-clamp level did not have a significant effect on long-term survival. Although both thoracic and hiatal clamping had no effect on mortality, postoperative respiratory complications, blood requirement, and intestinal ischemia were more pronounced in patients operated with thoracic clamping. Hiatal clamping is preferable for a safe postoperative period.
本研究的目的是确定膈上阻断和胸段阻断对术后结局及发病率的影响,以及影响死亡率和发病率的因素。对1993年至2005年间接受破裂腹主动脉瘤修复术的102例患者的记录进行回顾性评估。分别有72例和30例患者进行了膈上阻断和胸段阻断。通过单因素和多因素统计分析对两组患者的术后并发症和生存率进行比较评估。总体死亡率和医院死亡率分别为63例(61.8%)和24例(23.5%);两组之间无差异。胸段阻断组术后呼吸并发症、胃肠道并发症和输血需求更高。术前休克和肾缺血时间(>30分钟)被发现是医院死亡率的重要预测因素。术后肾衰竭是唯一独立的术后死亡预测因素。在随访期,心脏事件是晚期死亡的独立预测因素。如果排除医院死亡病例,5年和10年累积生存率分别为57.82±5.85%和38.16±6.97%。阻断水平对长期生存无显著影响。虽然胸段阻断和膈上阻断对死亡率均无影响,但胸段阻断手术患者的术后呼吸并发症、输血需求和肠道缺血更为明显。膈上阻断更有利于术后安全。