Use of an interferon-gamma based assay to assess bladder cancer patients treated with intravesical BCG and exposed to tuberculosis.
作者信息
Silverman M S, Reynolds D, Kavsak P A, Garay J, Daly A, Davis I
机构信息
University of Toronto, Ontario, Canada.
出版信息
Clin Biochem. 2007 Aug;40(12):913-5. doi: 10.1016/j.clinbiochem.2007.04.006. Epub 2007 Apr 27.
Abstract
OBJECTIVE
Compare the QuantiFERON-TB Gold In-Tube (QFT) assay and the tuberculin skin test (TST) in bladder cancer patients receiving high dose BCG therapy (BCG patients).
DESIGN AND METHODS
BCG patients and healthy visitors, both exposed to tuberculosis, were screened with a TST and QFT.
RESULTS
QFT-TST correlation was excellent in visitors, but poor in BCG patients. BCG therapy predicted a positive TST (p<0.001) but not a positive QFT (p=0.35).
DISCUSSION
The management of BCG patients was impacted, by measuring the QFT.
摘要
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