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反常栓塞显示重组组织型纤溶酶原激活剂在大面积肺栓塞中的作用速度。

Paradoxical embolus illustrating speed of action of recombinant tissue plasminogen activator in massive pulmonary embolism.

作者信息

Madani H, Ransom P A

机构信息

Royal Free NHS Trust Hospital, Pond Street, London NW3 2QG, UK.

出版信息

Emerg Med J. 2007 Jun;24(6):441. doi: 10.1136/emj.2006.045104.

DOI:10.1136/emj.2006.045104
PMID:17513552
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2658293/
Abstract

A case of a patient who presented with massive pulmonary embolism (PE) requiring thrombolysis with alteplase is reported. The subsequent presence of a patent foramen ovale and paradoxical embolism clinically demonstrated the speed of action of the recombinant tissue plasminogen activator. The advantage of this class of medication when considering the treatment options for a PE in an acute setting is highlighted.

摘要

报告了一例出现大面积肺栓塞(PE)需用阿替普酶进行溶栓治疗的患者。随后发现的卵圆孔未闭和反常栓塞在临床上证明了重组组织型纤溶酶原激活剂的作用速度。强调了在考虑急性肺栓塞的治疗方案时这类药物的优势。

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Paradoxical embolus illustrating speed of action of recombinant tissue plasminogen activator in massive pulmonary embolism.反常栓塞显示重组组织型纤溶酶原激活剂在大面积肺栓塞中的作用速度。
Emerg Med J. 2007 Jun;24(6):441. doi: 10.1136/emj.2006.045104.
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Paradoxical embolism: a rare complication of thrombolysis.
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本文引用的文献

1
Efficacy of thrombolytic agents in the treatment of pulmonary embolism.溶栓药物治疗肺栓塞的疗效
Eur Respir J. 2005 Nov;26(5):864-74. doi: 10.1183/09031936.05.00002505.
2
Peripheral ischemia caused by paradoxical embolization: an underestimated problem?反常栓塞所致外周缺血:一个被低估的问题?
Mt Sinai J Med. 2005 May;72(3):200-6.
3
Comparison of medical treatment with percutaneous closure of patent foramen ovale in patients with cryptogenic stroke.隐源性卒中患者药物治疗与经皮卵圆孔未闭封堵术的比较
J Am Coll Cardiol. 2004 Aug 18;44(4):750-8. doi: 10.1016/j.jacc.2004.05.044.
4
Percutaneous transcatheter closure of patent foramen ovale in patients with paradoxical embolism.卵圆孔未闭患者反常栓塞的经皮导管封堵术
Circulation. 2002 Aug 27;106(9):1121-6. doi: 10.1161/01.cir.0000027819.19722.ee.