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采用定制口腔内模具技术对头颈部癌进行高剂量率近距离放射治疗的经验。

Experience of high-dose-rate brachytherapy for head and neck cancer treated by a customized intraoral mold technique.

作者信息

Obinata Kenichi, Ohmori Keiichi, Shirato Hiroki, Nakamura Motoyasu

机构信息

Department of Dental Radiology, Hokkaido University Hospital, North-13 West-6, Kita-ku, Sapporo, 060-8516, Japan.

出版信息

Radiat Med. 2007 May;25(4):181-6. doi: 10.1007/s11604-007-0121-y. Epub 2007 May 28.

Abstract

Radiotherapy of head and neck cancer has become more successful with the advances in treatment modalities and use of a multidisciplinary approach. Higher quality treatment and a team approach to radiotherapy have thus been required for head and neck cancer. This study presents the clinical experience of high-dose-rate (HDR) brachytherapy for head and neck cancer treated by a customized intraoral mold technique. Two patients are reported for whom we created dental prostheses as the radiation carriers for HDR brachytherapy of their head and neck cancers. HDR brachytherapy with the dental prostheses reported here was feasible and effective for eradicating the head and neck cancer. It has been demonstrated that HDR brachytherapy using a customized intraoral technique can be a treatment option for patients who are not candidates for surgery or external irradiation. It is strongly suggested that specialized dentists are needed who are familiar with not only the anatomy and function of the head and neck region but also radiotherapy. Dental radiologists should take responsibility for constructing irradiation prostheses. If they do, they have the potential to improve the quality of life of patients who undergo radiotherapy for head and neck cancer.

摘要

随着治疗方式的进步和多学科方法的应用,头颈部癌的放射治疗变得更加成功。因此,对头颈部癌需要更高质量的治疗和放射治疗的团队方法。本研究介绍了通过定制口腔内模具技术对头颈部癌进行高剂量率(HDR)近距离放射治疗的临床经验。报告了两名患者,我们为他们制作了假牙作为其头颈部癌HDR近距离放射治疗的辐射载体。此处报告的使用假牙的HDR近距离放射治疗对头颈部癌的根除是可行且有效的。已经证明,使用定制口腔内技术的HDR近距离放射治疗可以成为不适合手术或外照射的患者的一种治疗选择。强烈建议需要不仅熟悉头颈部区域的解剖结构和功能,而且熟悉放射治疗的专业牙医。牙科放射科医生应负责构建放射治疗假体。如果他们这样做,他们有可能改善接受头颈部癌放射治疗患者的生活质量。

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