Farage Miranda, Elsner Peter, Maibach Howard
The Procter & Gamble Company, Winton Hill Business Center, Feminine Care Clinical Sciences, 6110 Center Hill Rd, Box 136, Cincinnati, OH 45224, USA.
Arch Gynecol Obstet. 2007 Jun;275(6):415-27. doi: 10.1007/s00404-006-0273-5. Epub 2006 Nov 25.
Modern disposable sanitary pads are becoming available worldwide. Regional differences in usage practices, ethnicity, and climate may influence their skin compatibility. Pad usage practices depend on culture, economics, and menstrual physiology. Daily usage is higher in Japan and but lower in Nigeria compared to North America or Western Europe. Evidence for ethnic differences in skin irritant susceptibility is not compelling. Dark skin may be less susceptible to certain irritants than fair skin; the Japanese may experience a higher degree of sensory irritation than Caucasians. Ambient conditions such as high temperature and humidity increase the skin temperature and skin surface moisture under sanitary pads by small but measurable amounts, causing no discernible skin irritation; vapor-permeable pad backings reduce these effects. Cold dry conditions, which can irritate exposed skin, may not affect vulvar skin to the same degree due to its elevated hydration and occlusion. To address the practical significance of these variables, results of prospective clinical trials of sanitary pads performed by industry and academic scientists in North America (Indiana), Mexico, Western Europe (Munich, Athens, Goteborg, Sweden), Eastern Europe (Kiev) and Africa (Abuja, Nigeria) were reviewed. Despite the diverse range of conditions, no significant adverse skin effects were observed with modern pads compared to traditional pad designs. Study participants generally preferred modern pads for performance and comfort.
现代一次性卫生巾在全球范围内都可获得。使用习惯、种族和气候方面的地区差异可能会影响它们与皮肤的兼容性。卫生巾的使用习惯取决于文化、经济和月经生理。与北美或西欧相比,日本的日使用量较高,但尼日利亚的日使用量较低。关于皮肤刺激性易感性方面种族差异的证据并不确凿。深色皮肤可能比浅色皮肤对某些刺激物的敏感性更低;日本人可能比白种人更容易出现感觉刺激。高温和高湿等环境条件会使卫生巾下的皮肤温度和皮肤表面湿度有小幅但可测量的升高,不会引起明显的皮肤刺激;透气的卫生巾背衬可减少这些影响。寒冷干燥的环境会刺激暴露在外的皮肤,但由于外阴皮肤的水合作用增强和闭塞作用,可能不会对其产生同等程度的影响。为了探讨这些变量的实际意义,我们回顾了北美(印第安纳)、墨西哥、西欧(慕尼黑、雅典、瑞典哥德堡)、东欧(基辅)和非洲(尼日利亚阿布贾)的行业和学术科学家进行的卫生巾前瞻性临床试验结果。尽管条件各不相同,但与传统卫生巾设计相比,现代卫生巾未观察到明显的不良皮肤影响。研究参与者普遍因性能和舒适度而更喜欢现代卫生巾。