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结膜下注射庆大霉素导致白内障手术后结膜水肿。

Postoperative conjunctival chemosis in cataract surgery caused by subconjunctival gentamicin injection.

作者信息

Pande M

机构信息

Department of Ophthalmology, Hull Royal Infirmary.

出版信息

Br J Ophthalmol. 1991 Nov;75(11):660-2. doi: 10.1136/bjo.75.11.660.

DOI:10.1136/bjo.75.11.660
PMID:1751459
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1042521/
Abstract

A prospective study of 75 patients undergoing cataract surgery was conducted to identify the cause of postoperative conjunctival chemosis seen in patients with cataracts in this department. The patients were split in three groups of 25 each. Group G patients were given a subconjunctival injection of gentamicin at the end of the cataract procedure; group W patients did not receive subconjunctival gentamicin, but a cellulose wick drain was used during the procedure; and Group GW patients received a subconjunctival injection of gentamicin and a wick drain was also used. The incidence, severity, and the duration of chemosis were observed in the three groups. Chemosis was seen only in groups G and GW, and the difference between the number of patients who received gentamicin and those who did not receive gentamicin was significant (p less than 0.001).

摘要

对75例接受白内障手术的患者进行了一项前瞻性研究,以确定该科室白内障患者术后结膜水肿的原因。患者被分为三组,每组25人。G组患者在白内障手术结束时接受结膜下注射庆大霉素;W组患者未接受结膜下庆大霉素注射,但手术过程中使用了纤维素引流条;GW组患者接受结膜下注射庆大霉素且也使用了引流条。观察三组结膜水肿的发生率、严重程度和持续时间。结膜水肿仅在G组和GW组出现,接受庆大霉素治疗的患者与未接受庆大霉素治疗的患者数量差异有统计学意义(p<0.001)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc10/1042521/3a1677b0ca40/brjopthal00573-0021-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc10/1042521/3a1677b0ca40/brjopthal00573-0021-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc10/1042521/3a1677b0ca40/brjopthal00573-0021-a.jpg

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引用本文的文献

1
The role of preservatives in the conjunctival toxicity of subconjunctival gentamicin injection.防腐剂在结膜下注射庆大霉素结膜毒性中的作用。
Br J Ophthalmol. 1992 Apr;76(4):235-7. doi: 10.1136/bjo.76.4.235.

本文引用的文献

1
Gentamicin penetration in human aqueous after subconjunctival injection.结膜下注射后庆大霉素在人房水中的渗透情况。
Indian J Ophthalmol. 1981 Oct;29(3):307-11.
2
Subconjunctival gentamicin.结膜下注射庆大霉素。
Br J Ophthalmol. 1971 Jul;55(7):478-80. doi: 10.1136/bjo.55.7.478.
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Penetration and systemic absorption of gentamicin after subconjunctival injection.结膜下注射后庆大霉素的渗透及全身吸收情况
Br J Ophthalmol. 1972 Aug;56(8):609-12. doi: 10.1136/bjo.56.8.609.
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Ocular penetration of subconjunctivally injected gentamicin, sisomicin and cephaloridine.
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Randomised single blind trial to compare the toxicity of subconjunctival gentamicin and cefuroxime in cataract surgery.比较白内障手术中结膜下注射庆大霉素和头孢呋辛毒性的随机单盲试验
Br J Ophthalmol. 1990 Dec;74(12):734-8. doi: 10.1136/bjo.74.12.734.