Bradbury A W, Adam D J, Makhdoomi K R, Stuart W P, Murie J A, Jenkins A M, Ruckley C V
Vascular Surgery Unit, University Department of Surgery, Royal Infirmary, Edinburgh, UK.
Br J Surg. 1998 May;85(5):645-7. doi: 10.1046/j.1365-2168.1998.00695.x.
This study reviews the results of infrarenal abdominal aortic aneurysm (AAA) surgery over 21 years (1 January 1976 to 31 December 1996).
A prospectively gathered database was analysed.
Infrarenal AAA repair was performed in 1515 patients: 492 (32.5 per cent) had elective repair of an asymptomatic AAA; 194 (12.8 per cent) had elective repair of a symptomatic AAA; 156 (10.3 per cent) had emergency repair of a symptomatic non-ruptured AAA; and 673 (44.4 per cent) had surgery for a ruptured AAA. The 30-day and/or same admission mortality rates were 6.1, 5.8, 14.1 and 37 per cent respectively. Operative mortality increased in all four groups over the study interval, although this only attained statistical significance in patients having elective repair of a symptomatic, non-ruptured AAA. There was a significant increase in the age of patients undergoing elective repair of an asymptomatic AAA, but not in the other three groups. There was also a significant increase in the proportion of straight 'tube' grafts inserted in all four groups.
It remains the minority of patients who have elective operation before the onset of symptoms and/or rupture. Despite anaesthetic and surgical specialization, the results of AAA repair have not improved over the past two decades. Operative mortality may be increasing, possibly because of the increasing age and associated comorbidity of the patients presenting to this unit.
本研究回顾了21年间(1976年1月1日至1996年12月31日)肾下腹主动脉瘤(AAA)手术的结果。
对前瞻性收集的数据库进行分析。
1515例患者接受了肾下腹主动脉瘤修复术:492例(32.5%)为无症状AAA的择期修复;194例(12.8%)为有症状AAA的择期修复;156例(10.3%)为有症状未破裂AAA的急诊修复;673例(44.4%)为破裂AAA的手术治疗。30天和/或同一住院期间的死亡率分别为6.1%、5.8%、14.1%和37%。在研究期间,所有四组的手术死亡率均有所上升,尽管仅在有症状未破裂AAA择期修复的患者中达到统计学显著性。无症状AAA择期修复患者的年龄显著增加,但其他三组未增加。所有四组中植入直“管”状移植物的比例也显著增加。
在症状出现和/或破裂之前接受择期手术的患者仍占少数。尽管有麻醉和手术专业化,但在过去二十年中,AAA修复的结果并未改善。手术死亡率可能在上升,这可能是由于到本单位就诊患者的年龄增加以及合并症增多。