van Leeuwen Theo, Been Pieter, van Herten Marieke, Zwarts Frans, Maassen Ben, van der Leij Aryan
Faculty of Behavioral and Social Sciences, Department of Special Education, University of Amsterdam, Amsterdam, The Netherlands.
Neuroreport. 2007 Jun 11;18(9):857-61. doi: 10.1097/WNR.0b013e3280c1e2bf.
Cortical auditory categorization was assessed in 2-month-old infants at genetic risk for dyslexia and controls. Manipulated /bAk/ and /dAk/ speech stimuli were used as frequently presented standards. The neuroelectric brain responses of the control infants were highly sensitive to the phoneme boundary that separated these stimuli, but the infants at risk showed no signs of cortical categorical perception. Cortical sources of the responses were predominantly found in the left hemisphere for the control infants, but mainly in the right hemisphere for the infants at risk. The results demonstrate that impaired categorical perception in dyslexia is already present in infants at risk for the disorder.
对有诵读困难遗传风险的2个月大婴儿和对照组婴儿进行了皮质听觉分类评估。使用经过处理的/bAk/和/dAk/语音刺激作为频繁呈现的标准刺激。对照组婴儿的神经电脑反应对分隔这些刺激的音素边界高度敏感,但有风险的婴儿没有表现出皮质分类感知的迹象。对照组婴儿的反应皮质源主要位于左半球,而有风险的婴儿主要位于右半球。结果表明,诵读困难中受损的分类感知在有该疾病风险的婴儿中已经存在。