婴儿期和儿童期葡萄糖、尿素和肌酐的腹膜转运动力学

Peritoneal transport kinetics of glucose, urea, and creatinine during infancy and childhood.

作者信息

Schröder C H, van Dreumel M J, Reddingius R, Theeuwes A G, Willems H L, de Jong M C, Monnens L A

机构信息

Department of Pediatrics, St. Radboud University Hospital, Nijmegen, The Netherlands.

出版信息

Perit Dial Int. 1991;11(4):322-5.

PMID:1751597

Abstract

Peritoneal handling of glucose and metabolites is reported to be higher in young children treated with CAPD than in older children. Reference curves for the standardized peritoneal equilibration test (PET) are not available for younger ages. The present study describes the results of the PET in 19 children (mean age 5.0 years, ranging from 0.3-15) during the first month of CAPD treatment. No age dependency for the handling of glucose, urea, and creatinine could be established when the group was subdivided into 1. children below the age of 3 years, and 2. children above that age. There was, however, a significant correlation between equilibration of creatinine and age, indicating more rapid equilibration at younger ages.

摘要

据报道，接受持续性非卧床腹膜透析（CAPD）治疗的幼儿对葡萄糖和代谢产物的腹膜处理能力高于大龄儿童。目前尚无针对低龄儿童的标准化腹膜平衡试验（PET）参考曲线。本研究描述了19名儿童（平均年龄5.0岁，范围为0.3 - 15岁）在CAPD治疗第一个月期间的PET结果。当将该组儿童分为1. 3岁以下儿童和2. 3岁以上儿童时，未发现葡萄糖、尿素和肌酐处理存在年龄依赖性。然而，肌酐平衡与年龄之间存在显著相关性，表明低龄儿童的平衡速度更快。